A significant challenge in the production of Earth observation satellites is the precise alignment of the telescope optical components. We have developed a strategy to perform automated alignment of two-mirror telescopes for use in a realistic factory-based setting. A Ritchey-Chrétien telescope was used as an example. The secondary mirror was mounted on a high precision hexapod and its misalignment inferred from the Zernike coefficients for tilt, defocus, and coma, as measured by a phase-shifting interferometer. The required corrections to the position of the secondary mirror were implemented using an integral controller and alignment was achieved within minutes, compared to within days when using a manual alignment process. The Zernike coefficient for each aberration was reduced to within one standard deviation of the fluctuations due to residual instability (48 nm).
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http://dx.doi.org/10.1364/AO.58.007388 | DOI Listing |
J Hand Surg Am
January 2025
Hand and Upper Extremity Division of Plastic and Reconstructive Surgery, University of California Davis, Sacramento, CA.
Purpose: Current technologies to define the zone of acute peripheral nerve injury intraoperatively are limited by surgical experience, time, cumbersome electrodiagnostic equipment, and interpreter reliability. In this pilot study, we evaluated a real-time, label-free optical technique for intraoperative nerve injury imaging. We hypothesize that fluorescence lifetime imaging (FLIm) will detect a difference between the time-resolved fluorescence signatures for acute crush injuries versus uninjured segments of peripheral nerves in sheep.
View Article and Find Full Text PDFJ Neural Transm (Vienna)
January 2025
Laboratory of Biological Psychiatry, Institute of Mental Health, Tianjin Anding Hospital, Mental Health Center of Tianjin Medical University, 13 Liulin Road, Tianjin, 300222, China.
Bipolar disorder (BD) frequently coexists with anxiety disorders, creating complex challenges in clinical therapy and management. This study investigates the prevalence, prognostic implications, and treatment strategies for comorbid BD and anxiety disorders. High comorbidity rates, particularly with generalized anxiety disorder, underscore the necessity of thorough clinical assessments to guide effective management.
View Article and Find Full Text PDFSci Rep
January 2025
University of Ghana, P.O. Box 134, Legon-Accra, Ghana.
Sentiment analysis has become a difficult and important task in the current world. Because of several features of data, including abbreviations, length of tweet, and spelling error, there should be some other non-conventional methods to achieve the accurate results and overcome the current issue. In other words, because of those issues, conventional approaches cannot perform well and accomplish results with high efficiency.
View Article and Find Full Text PDFApoptosis
January 2025
Department of Pathology, Fudan University Shanghai Cancer Center, Shanghai, China.
Cancer-associated fibroblasts (CAFs) significantly influence tumor progression and therapeutic resistance in colorectal cancer (CRC). However, the distributions and functions of CAF subpopulations vary across the four consensus molecular subtypes (CMSs) of CRC. This study performed single-cell RNA and bulk RNA sequencing and revealed that myofibroblast-like CAFs (myCAFs), tumor-like CAFs (tCAFs), inflammatory CAFs (iCAFs), CXCL14CAFs, and MTCAFs are notably enriched in CMS4 compared with other CMSs of CRC.
View Article and Find Full Text PDFSci Rep
January 2025
Shandong Yankuang Intelligent Manufacturing Co., Jining, 272000, China.
The hydraulic column is a core component in the coal mine support system, however, the real-time monitoring of the hydraulic column during the service process of the hydraulic support faces challenges. To address these issues, a high-precision stress mapping method of hydraulic column is proposed. The hydraulic column loss function was constructed to guide the data-driven model training, and the cylinder stress mechanism model was established by using the elastic-plastic theory of thick-walled cylinder.
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