A fiber surface-enhanced Raman scattering (SERS) probe based on the depressed double cladding fiber (DDCF) is demonstrated. Due to the depressed cladding, the optical field distribution of the DDCF is more approachable to the outer surface than that of a no core fiber without depressed cladding, improving the excitation efficiency for generating Raman scattered light. The cladding diameter of the DDCF is only 80 µm, which is smaller than the core diameter (105 µm) of the input multimode fiber (MMF). This small cladding diameter ensures a well collection coupling from the DDCF to the MMF. The impact of the DDCF length on the performance of the probe is investigated. Raman spectra of Rhodamine 6G (R6G) are measured using the DDCF-based SERS probe, which is embedded in a microfluidic chip. The all-fiber optical path configuration realizes an all-fiber Raman detection system that is stable, portable, and convenient to operate. Such results confirm the applicability of the DDCF-based fiber probe in the all-fiber SERS detection area and indicate that the proposed SERS probe renders a new scheme for optimal design of the fiber SERS probe structure.
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http://dx.doi.org/10.1364/AO.58.007929 | DOI Listing |
ACS Nano
January 2025
Department of Chemistry, Cape Breton University, Sydney, Nova Scotia B1P 6L2, Canada.
Reactive oxygen species (ROS) play fundamental roles in various biological and chemical processes in nature and industries, including cell signaling, disease development and aging, immune defenses, environmental remediation, pharmaceutical syntheses, metal corrosion, energy production, etc. As such, their detection is of paramount importance, but their accurate identification and quantification are technically challenging due to their transient nature with short lifetimes and low steady-state concentrations. As a highly sensitive and selective analytical technique, surface-enhanced Raman spectroscopy (SERS) is promising for detecting ROS in real-time, enabling in situ monitoring of ROS-involved electrochemical and biochemical events with exceptional resolution.
View Article and Find Full Text PDFAnal Methods
January 2025
Key Laboratory of Oil and Gas Fine Chemicals Ministry of Education, Xinjiang Uyghur Autonomous Region, School of Chemical Engineering and Technology, Xinjiang University, Urumqi 830017, Xinjiang, China.
The unreasonable use of organic dye leads to excessive residues in environmental water, which seriously threatens human health and the natural environment. In this paper, a spherical flower-like magnetic FeO@CoNi layered double hydroxide@silver nanoparticle (FeO@CoNi LDH@Ag NPs) SERS substrate was successfully fabricated electrostatic self-assembly and applied for the sensitive detection of methylene blue (MB) in environmental water. The rapid concentration and separation of the SERS substrate from the water sample could be achieved using an external magnet.
View Article and Find Full Text PDFJ Colloid Interface Sci
December 2024
The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xi'an 710049, People's Republic of China. Electronic address:
The precise design and synthesis of Au and Ag composite nanomaterials can provide them with richer plasmonic modes, resulting in enhanced optical properties. Here, a novel strategy was demonstrated to control the selective deposition of Ag at different positions of Au triangular nanoprisms (Au TNPs). 1,4-benzenedithiol (BDT) was selectively absorbed in different positions of Au TNPs which made Ag selectively deposited on Au TNPs.
View Article and Find Full Text PDFJ Phys Chem Lett
December 2024
Biomolecular Physics Department, Faculty of Physics, Babeş-Bolyai University, 1 M. Kogalniceanu Str., 400084 Cluj-Napoca, Romania.
Surface-enhanced Raman spectroscopy (SERS) has emerged as a powerful tool for analyzing nucleic acids due to its exceptional sensitivity and specificity. This study rigorously investigates not only the impact of polyA strands of different lengths (, 5, 10, 15, and 20 adenine bases) but also their distinct grafting strategy (SH at 5' and NH at 5' end) on the SERS signal of DNA strand using synthesized gold nanoparticles (AuNPs) on graphene oxide sheets (GO-AuNPs). By comparing the thiol vs amine bonding onto the GO-AuNP nanoplatform, we found a strong correlation between the adenine peak intensity at 732 cm and the strand length for both grafting methods (SH at 5' end or NH at 5' end).
View Article and Find Full Text PDFAnal Chem
December 2024
Phenikaa University Nano Institute (PHENA), Phenikaa University, Hanoi 12116, Vietnam.
Surface-enhanced Raman spectroscopy (SERS) is a powerful analytical technique, yet it faces challenges with certain probe molecules exhibiting weak or inactive signals, limiting their applicability. In a recent study, we investigated this phenomenon using a set of four probe molecules─chloramphenicol (CAP), 4-nitrophenol (4-NP), amoxicillin (AMX), and furazolidone (FZD)─deposited on Ag-based nanostructured SERS substrates. Despite being measured under identical conditions, CAP and 4-NP exhibited SERS activity, while AMX and FZD did not.
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