Objectives: This study was performed to examine the effects of the Korean medicine healthcare program on stroke-related factors and self-care enhancement.
Methods: This study was a quasi-experimental, pretest-posttest nonequivalent control group design study ( = 58 participants), with 28 in the treatment group (Korean medicine health care program) and 30 in the control group (no intervention). The program was conducted twice a week for 2 hours, for a total of 12 weeks.
Results: There were statistically significant differences in systolic ( = 0.005) and diastolic blood pressure ( = 0.006), cholesterol ( < 0.001), blood glucose ( < 0.001), self-esteem ( = 0.001), self-efficacy ( < 0.001), health perception ( < 0.001), and the health behavior ( < 0.001) between the experimental group and the control group.
Conclusion: Thus, the Korean medicine healthcare program was effective in managing stroke-related factors and enhancing self-care, and should be actively used to develop community health promotion strategies to prevent strokes and prepare long-term measures.
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http://dx.doi.org/10.24171/j.phrp.2019.10.5.07 | DOI Listing |
Lung
January 2025
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Korea University Guro Hospital, 148, Gurodong-ro, Guro-gu, Seoul, 08308, Republic of Korea.
Purpose: To determine effects of colonization with multidrug-resistant bacteria (MDRB) in general wards on characteristics, treatment, and prognosis of hospital-acquired pneumonia (HAP).
Methods: This was a multicenter retrospective cohort study of patients with HAP admitted to 16 tertiary or university hospitals in Korea from July 2019 to December 2019. From the entire cohort, patients who developed pneumonia in general wards with known colonization status before the onset of pneumonia were included in this study.
Alzheimers Dement
December 2024
Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.
Background: With a rapidly aging population, South Korea anticipates a surge in Alzheimer disease (AD). However, the genetic basis of AD in Koreans is not well understood.
Method: We sequenced the genomes of 3,540 Koreans (1,583 AD cases and 1,957 controls) older than age 60 and performed a genome-wide association study (GWAS) of AD using logistic regression models that included covariates for age, sex, five ancestry principal components, and an empirical genetic relationship matrix.
Alzheimers Dement
December 2024
Interdisciplinary program of cognitive science, Seoul National University College of Humanities, Seoul, Korea, Republic of (South).
Background: Large-scale genome-wide association studies (GWAS) of Alzheimer's disease (AD) from European ancestry identified many genetic variants associated with clinical diagnosis of AD dementia. However, it remains unclear whether these AD-related variants are associated with AD biomarkers, particularly hippocampal atrophy, a well-known neurodegeneration biomarker of AD in a Korean population. In this study, we investigated the association between known AD risk single nucleotide polymorphisms (SNPs) and hippocampal atrophy along the AD continuum in older Korean adults.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of (South).
Background: Previous Alzheimer's disease GWAS studies were mostly based on the European population, and the β-amyloid (Aβ) status was not considered. We performed a meta-GWAS using East Asian and European genomics data and performed prediction of Aβ status using the identified variant. We utilized single-cell transcriptome data to identify the differentially expressed gene that is affected by the variant.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Konkuk University School of Medicine, Chungju, Chungbuk-do, Korea, Republic of (South).
Background: The purpose of this study was to compare gait pattern and cognitive function among elderly patients with Alzheimer's Disease (AD), elderly people with Mild Cognitive Impairment (MCI), and Healthy Controls (HC).
Method: Twenty three elderly patients participated: 25 AD (78.4±6.
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