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Updated appropriate use criteria for amyloid and tau PET: A report from the Alzheimer's Association and Society for Nuclear Medicine and Molecular Imaging Workgroup.
Alzheimers Dement
January 2025
Center for Alzheimer Research and Treatment, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Introduction: The Alzheimer's Association and the Society of Nuclear Medicine and Molecular Imaging convened a multidisciplinary workgroup to update appropriate use criteria (AUC) for amyloid positron emission tomography (PET) and to develop AUC for tau PET.
Methods: The workgroup identified key research questions that guided a systematic literature review on clinical amyloid/tau PET. Building on this review, the workgroup developed 17 clinical scenarios in which amyloid or tau PET may be considered.
Updated consensus guidelines for management of moderate-to-severe atopic dermatitis in Singapore: Integrating biologics, Janus kinase inhibitors and conventional therapies.
Ann Acad Med Singap
November 2024
Department of Dermatology, Singapore General Hospital, Singapore.
Article Synopsis
- Several new therapies, including biologics and JAK inhibitors, have been approved for treating atopic dermatitis (AD) in Singapore since 2016, leading to an update of treatment guidelines for moderate-to-severe cases.
- A modified Delphi panel with 12 dermatologists conducted surveys to reach consensus on treatment statements, resulting in agreement on 43 statements across different treatment categories.
- The study highlights dupilumab and JAK inhibitors as potential first-line treatments for certain patients with moderate-to-severe AD, and indicates that further updates to the guidelines may be necessary as new information emerges.
Article Synopsis
- A small working group was formed to modernize the Methodological Expectations for Campbell Collaboration Intervention Reviews (MECCIR) based on feedback indicating that the previous version was too lengthy and challenging to use.
- The goal was to create a more concise and relevant checklist that includes guidance for both conducting and reporting reviews, applicable to various types including quantitative non-intervention reviews.
- The development process included multiple meetings to discuss and refine the checklist, aligning it with existing standards, and incorporated feedback from Campbell members to ensure it was comprehensive yet user-friendly.
Monitoring and integrated care coordination of patients with alpha-mannosidosis: A global Delphi consensus study.
Mol Genet Metab
August 2024
International Center for Lysosomal Disorders (ICLD), University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address:
Introduction: Current literature lacks consensus on initial assessments and routine follow-up care of patients with alpha-mannosidosis (AM). A Delphi panel was conducted to generate and validate recommendations on best practices for initial assessment, routine follow-up care, and integrated care coordination of patients with AM.
Methods: A modified Delphi method involving 3 rounds of online surveys was used.
Engaging With Health Consumers in Scientific Conferences-As Partners not Bystanders.
Health Expect
August 2024
School of Public Health, The University of Sydney, Sydney, New South Wales, Australia.
Introduction: It is now widely recognised that engaging consumers in research activities can enhance the quality, equity and relevance of the research. Much of the commentary about consumer engagement in research focuses on research processes and implementation, rather than dissemination in conference settings. This article offers reflections and learnings from consumers, researchers and conference organisers on the 12th Health Services Research Conference, a biennial conference hosted by the Health Services Research Association of Australia and New Zealand (HSRAANZ).
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