AI Article Synopsis
- * The study involved crossing two wasp lines with different venom, generating variability and observing changes over 10 generations on different host strains.
- * Results showed that venom composition evolved quickly depending on the host, with proteins beneficial for one host potentially being harmful for another, highlighting the wasps' ability to adapt to new hosts and the importance of studying specific venom proteins for successful parasitism.
Article Abstract
Parasitoid wasps rely primarily on venom to suppress the immune response and regulate the physiology of their host. Intraspecific variability of venom protein composition has been documented in some species, but its evolutionary potential is poorly understood. We performed an experimental evolution initiated with the crosses of two lines of of different venom composition to generate variability and create new combinations of venom factors. The offspring were maintained for 10 generations on two strains of differing in resistance/susceptibility to the parental parasitoid lines. The venom composition of individuals was characterized by a semi-automatic analysis of 1D SDS-PAGE electrophoresis protein profiles whose accuracy was checked by Western blot analysis of well-characterized venom proteins. Results made evident a rapid and differential evolution of the venom composition on both hosts and showed that the proteins beneficial on one host can be costly on the other. Overall, we demonstrated the capacity of rapid evolution of the venom composition in parasitoid wasps, important regulators of arthropod populations, suggesting a potential for adaptation to new hosts. Our approach also proved relevant in identifying, among the diversity of venom proteins, those possibly involved in parasitism success and whose role deserves to be deepened.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891688 | PMC |
| http://dx.doi.org/10.3390/toxins11110629 | DOI Listing |
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