bacteremia is one of the most frequent and severe bacterial infections worldwide. The increased incidence of infections with a diverse pattern of protein A () types across different geographic regions is a global challenge. This study investigated a novel type of methicillin-resistant in a clinically isolated specimen. A total of 109 clinical samples were subjected to 19 sets of antimicrobial susceptibility testing using the Kirby-Bauer disk diffusion method. Molecular typing was performed with protein A () and multi-locus sequence types (MLST) via polymerase chain reaction and sequencing. The methicillin-resistant samples in our study accounted for 55.05% (60/109) of the total. A novel type was detected in five (5/60) strains. This 2 isolate was identified in antimicrobial susceptibility tests of 15 kinds of antibiotics. Antibiotic resistance genes included , , and Eleven samples were classified as , , , , five unknown types (new types), and undefined MLST (novel MLST). We report a high prevalence rate of methicillin-resistant samples in our country. Additionally, novel 2, MLST ST4613, and clonal compact CC5-type strains (T1:M1:B1:B1:M1:E1:K1, r26:r17:r34:r34:r17:r13:r16, mlst;1:4:1:4:559:495:10) showing multidrug resistance were identified among samples.
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| http://dx.doi.org/10.3390/antibiotics8040202 | DOI Listing |
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