AI Article Synopsis
- N-methyl fatty hydroxamic acid (N-MFHA) was synthesized from ketapang seed oil using an immobilized lipase in a biphasic medium of hexane and water.
- The synthesis process was optimized by examining factors like incubation time, enzyme amount, and temperature, with the best results achieved at 25 hours of incubation, 40 °C, and a 1:100 ratio of enzyme to oil.
- Under these optimal conditions, about 59.7% of the oil was successfully converted into N-MFHA, showcasing the compound's potential for various applications due to its chelating and biological properties.
Article Abstract
N-methyl fatty hydroxamic acid (N-MFHA), which is a derivative of hydroxamic acid (HA), was synthesized from ketapang seed oil ( L.). In general, HAs have wide applications due to their chelating properties and biological activities. N-MFHAs were synthesized using immobilized lipase (Lipozyme TL IM) in biphasic medium which was the ketapang seed oil dissolved in hexane and N-methylhydroxylamine dissolved in water. The products were characterized through color testing and FT-IR spectroscopy after purification. Various factors affecting the enzyme activity investigated in the study included the effect of incubation time, the amount of lipase used, and the temperature. On the basis of the results, the optimum conditions for the synthesis of N-MFHA obtained are 25 h of incubation time, a temperature of 40 °C, and a ratio of 1:100 for the amount of enzyme (g)/oil (g). At the optimum conditions of the reaction, 59.7% of the oils were converted to N-MFHA.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6865262 | PMC |
| http://dx.doi.org/10.3390/molecules24213895 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!