Chemical Constituents of Stems and Leaves of L. and Its Fingerprint.

Molecules

Dalian Wuzhou Holy Herb Scientific and Techonological Co. Ltd., Dalian 116600, China.

Published: October 2019

L. is a widely cultivated herbal medicinal plant in China and other countries. In this study, two new 2, 3-dihydrobenzofuran glucosides (, ) and fourteen known metabolites (-) were isolated from the stems and leaves of (SLT). The chemical structures of the isolated compounds were characterized comprehensively based on one- and two-dimensional NMR spectroscopy and high resolution mass spectrometry. Absolute configurations of compounds and were determined by ECD calculations. Compounds and exhibited moderate in vitro inhibitory activities against human gastric cancer cell lines (AGS) with IC values of 41.20 μmol/L and 30.43 μmol/L, respectively. The fingerprint profiles of stems and leaves of with three color types of flowers (Janie Yellow Bright, Jinmen Orange, Shouyao Red and Yellow color) were established by high-performance liquid chromatography (HPLC). Ten different batches of stems and leaves were examined as follow: Shouyao Red and Yellow color (1, 2, 3), Janie Yellow Bright (4, 5, 6, 7) and Jinmen Orange (8, 9, 10). Twenty-two common peaks were identified with similarity values ranging from 0.910 to 0.977. Meanwhile, the average peak area of SLT in the three types of flowers was different and it was the highest in Janie Yellow Bright.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864839PMC
http://dx.doi.org/10.3390/molecules24213911DOI Listing

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