AI Article Synopsis
- Dental caries is a highly communicable disease, and the study investigates how salivary antioxidants and oxidative stress relate to its prevention and progression.
- Water samples were collected from 100 university students, split into caries-active and caries-free groups, to evaluate levels of various antioxidants using a spectrophotometric method.
- Results showed that caries-active students had higher levels of several antioxidants but lower superoxide dismutase, indicating that salivary antioxidants significantly impact oral health.
Article Abstract
Background And Aim: Dental caries is a communicable and the most prevalent infectious disease worldwide. Salivary oxidative stress and antioxidants may play a pivotal role in caries prevention, progression and pathogenesis. In this study, salivary superoxide dismutase, peroxidase, glutathione peroxidase, catalase and uric acid levels were evaluated in dental caries.
Materials And Methods: One hundred male and female students in two groups (n=50) were subdivided into caries-active and caries-free (25) groups. Whole saliva samples were collected in the morning, and the salivary antioxidant levels were measured by a spectrophotometric assay. The data were analyzed using SPSS.
Results: The caries-active group had higher peroxidase, uric acid, catalase and glutathione peroxidase levels, and lower superoxide dismutase level as compared to the caries-free group. The comparison between males and females showed lower peroxidase, catalase and uric acid levels and higher glutathione peroxidase levels in the female group.
Conclusion: The caries-active group had altered salivary antioxidant levels. Therefore, it was concluded that salivary antioxidants have significant effects on oral and dental health.
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| http://dx.doi.org/10.2174/1871526519666191031100432 | DOI Listing |
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