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IgG Fc glycosylation as an axis of humoral immunity in childhood. | LitMetric
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IgG Fc glycosylation as an axis of humoral immunity in childhood.

Hao D Cheng Irit Tirosh Noortje de Haan Henning Stöckmann Barbara Adamczyk Ciara A McManus Róisín O'Flaherty Gordon Greville Radka Saldova Francisco A Bonilla Luigi D Notarangelo Gertjan J Driessen Ingrid A Holm Pauline M Rudd Manfred Wuhrer Margaret E Ackerman Peter A Nigrovic

J Allergy Clin Immunol

Division of Immunology, Boston Children's Hospital, Boston, Mass; Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Boston, Mass. Electronic address:

Published: February 2020

IgG Fc glycans were characterized in 225 healthy children and 40 children with unexplained recurrent respiratory infections, revealing age-dependent variation and suggesting a role for IgG glycosylation in immunocompetence.

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 Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010538PMC
http://dx.doi.org/10.1016/j.jaci.2019.10.012DOI Listing

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