Colostrum of goat is a well-known nutritional source of animal product, which is attributed to innumerable nutritional properties. To enrich nutritional resources for understanding various nutritional values of animal product at high altitude, chemometric analysis of antioxidant and mineral element study was carried out by comparing antioxidants capacity, free radical scavenging activity, and certain mineral elements in colostrums of native and non-native goat breeds. Colostrum samples were collected from native Changthangi (CNG) and non-native Sirohi (SIRO) goat breeds, situated at naturally exposed high altitude of 3505.2 m above mean sea level. The antioxidant of samples was measured by ferric reducing ability of plasma (FRAP) and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) activity assay, and mineral elemental quantification of Fe, Mg, Mn, Zn, Co, Cu, K, Ca, B, Ni, and Cr was performed using ICP-OES. The values of FRAP, DPPH, and Fe, Mg, Mn, Zn, Co, Cu, K, and Ca in colostrums of native goat breed was significantly (p ≤ 0.05) higher than the non-native goat. These data conclude that high altitude native goat has more antioxidant and mineral elements in colostrum than non-native colostrum. This study could provide a basis for establishing the role of colostrum supplements as a natural source to strengthen the endurance to modalities for the survival of newborn kids of goat within the native high altitude environment. This is the first report of a comparative chemometric analysis of colostrums of goat species and can be utilized to characterize the nutritional aspect of animal product with unique antioxidant and mineral nutrients composition in colostrum of goat.
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http://dx.doi.org/10.1007/s12011-019-01940-y | DOI Listing |
Cornea
January 2025
Department of Ophthalmology, Rothschild Foundation, Paris, France; and.
Purpose: The purpose of this study was to investigate the effect of hypoxia and hypobaric conditions on refraction and central corneal thickness on healthy corneas during an ascent without oxygen supplementation above 7000 m (23 000 ft).
Methods: Twelve multinational mountaineers were included in a prospective observational cohort study during an expedition to the Korzhenevskoi Peak (7105 m). The two patients excluded from the study had a history with keratoconus or were current wearers of rigid contact lenses.
Background: Due to the unique geographical and climatic conditions in Nagqu (Tibet), the blood station laboratory was only fully established and accredited by 2020. This study validated the performance of the laboratory's blood screening system and analyzed recent trends in blood donation and screening effectiveness.
Methods: Various serum samples were used to assess the performance of hepatitis B, hepatitis C, HIV, and syphilis tests, both serological and nucleic acid tests.
Background: Due to environmental hypoxia on the high-altitude local residents often exhibit a compensative increase in hemoglobin concentration to maintain the body's oxygen supply. In certain people, the number of red blood cells continues to grow, resulting in high altitude polycythemia (HAPC) which is characterized by headache, disorientation, sleeplessness, and bone discomfort. HAPC is often associated with multiple complications, of which lower extremity arteriosclerosis obliterans (LEASO) is rare.
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January 2025
Chengdu Engineering Corporation Limited, Chengdu, 610072, China.
The proportion of railway high-altitude buried tunnels in complex and dangerous mountainous areas in southwest China is exceptionally high. With the characteristics of suddenness, intermittency, instantaneousness, and destruction, inrushinrushing and collapse is one of the main risks in the tunnel construction process. Therefore, in the design and construction process of tunnels in Hengduan Mountain area, it is very important to identify the mechanism of sudden s inrushing and collapse risks, predict the spatial location and scale of possible inrushing and collapse, and formulate corresponding tunnel design and construction response measures.
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January 2025
Department of Environmental Analytical Chemistry, Helmholtz Centre for Environmental Research (UFZ), 04318, Leipzig, Germany.
Nanoplastics are suspected to pollute every environment on Earth, including very remote areas reached via atmospheric transport. We approached the challenge of measuring environmental nanoplastics by combining high-sensitivity TD-PTR-MS (thermal desorption-proton transfer reaction-mass spectrometry) with trained mountaineers sampling high-altitude glaciers ("citizen science"). Particles < 1 μm were analysed for common polymers (polyethylene, polyethylene terephthalate, polypropylene, polyvinyl chloride, polystyrene and tire wear particles), revealing nanoplastic concentrations ranging 2-80 ng mL at five of 14 sites.
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