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Sister Mary Joseph's nodule in endometrial carcinoma: A case report. | LitMetric

Sister Mary Joseph's nodule in endometrial carcinoma: A case report.

World J Clin Cases

Third Department of Oncology, Hebei General Hospital, Shijiazhuang 050051, Hebei Province, China.

Published: October 2019

AI Article Synopsis

  • Sister Mary Joseph's nodule (SMJN) is a rare condition, often associated with malignant abdominal tumors, and is linked to a poor prognosis, particularly with endometrial carcinoma.
  • A 75-year-old woman with a history of endometrial cancer developed a painless umbilical mass after chemotherapy; treatment was adjusted, leading to a reduction in the tumor and improved quality of life.
  • The presence of an umbilical mass necessitates consideration of SMJN, especially due to the poor prognosis it indicates in patients with advanced endometrial cancer, highlighting the need for careful treatment planning.

Article Abstract

Background: Sister Mary Joseph's nodule (SMJN) is rare and may occur independently or simultaneously with malignant tumors in the abdominal cavity. It has a poor prognosis. Endometrial carcinoma is the most common malignant tumor in the upper segment of the female reproductive tract; however, it rarely occurs with SMJN. We here report a case of endometrial carcinoma with SMJN.

Case Summary: A 75-year-old woman was diagnosed with endometrial cancer > 2 years ago. After multiple cycles of chemotherapy, an obvious but painless umbilical mass was detected 2 wk before admission. The patient did not undergo surgical treatment but received chemotherapy, which was different from previous chemotherapy, for three consecutive cycles after discovery of umbilical metastases. Currently, the umbilical metastatic tumor has reduced, and the quality of life of the patient has significantly improved.

Conclusion: Once the umbilical mass is found, the possibility of SMJN should be considered. We should also take into account the poor prognosis of endometrial carcinoma complicated with umbilical metastasis, especially in patients with advanced tumors, and it is important to choose an appropriate treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819280PMC
http://dx.doi.org/10.12998/wjcc.v7.i20.3358DOI Listing

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