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Molecular characterization of the receptor in larvae. | LitMetric

Larval therapy with is a promising strategy in wound healing. Axon guidance molecules play vital roles during the development of the nervous system and also regulate the capacity of neuronal restoration in wound healing. , one of the proteins that larvae secrete, plays a useful role in cell migration and nerve tissue regeneration. The combines with a signal and transmits the signal from one side of the membrane to the other side, initiating a change in cell activity. In the current study, we identified the full length of the mRNA in using different sets of primers, including exon junction and specific region primers. The coding sequence (CDS) of the was sequenced and identified to include 633 base-pair nucleic acids, and BLAST analysis on its nucleotide sequence revealed 96% identity with the netrin-1 . The protein residue included 210 amino acids (aa) and coded for a protein with 24 kD weight. This gene lacked the signal peptide. Furthermore, the UPA domain is conserved in . It lied at the interval of 26-131 aa. We identified the CDS of in . It could be applied to research activities implementing a new essential component design in wound healing.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803787PMC
http://dx.doi.org/10.3934/genet.2019.3.46DOI Listing

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