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The role of exploration and exploitation in primate communication.
Proc Biol Sci
January 2025
DFG Centre for Advanced Studies 'Words Bones, Genes, Tools', University of Tübingen, Rümelinstrasse 23, Tübingen 72070, Germany.
The concepts of social learning and exploration have been central to debates in comparative cognition research. While their roles in the origins of human cumulative culture on the one hand and creativity on the other have been highlighted, the two concepts have mostly been studied separately. In this article, we examine the relationship between adopting similar or different behaviours within a group, focusing on how exploration and exploitation shape primate communication systems.
View Article and Find Full Text PDFIntegration of CRISPR/dCas9-Based methylation editing with guide positioning sequencing identifies dynamic changes of mrDEGs in breast cancer progression.
Cell Mol Life Sci
January 2025
Institutes of Biomedical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.
Dynamic changes in DNA methylation are prevalent during the progression of breast cancer. However, critical alterations in aberrant methylation and gene expression patterns have not been thoroughly characterized. Here, we utilized guide positioning sequencing (GPS) to conduct whole-genome DNA methylation analysis in a unique human breast cancer progression model: MCF10 series of cell lines (representing benign/normal, atypical hyperplasia, and metastatic carcinoma).
View Article and Find Full Text PDFResViT FusionNet Model: An explainable AI-driven approach for automated grading of diabetic retinopathy in retinal images.
Comput Biol Med
January 2025
Department of Creative Technologies, Air University, Islamabad, 44000, Pakistan. Electronic address:
Background And Objective: Diabetic Retinopathy (DR) is a serious diabetes complication that can cause blindness if not diagnosed in its early stages. Manual diagnosis by ophthalmologists is labor-intensive and time-consuming, particularly in overburdened healthcare systems. This highlights the need for automated, accurate, and personalized machine learning approaches for early DR detection and treatment.
View Article and Find Full Text PDFFrontline professionals' experiences of navigating boundaries in a layered care and support system for individuals with complex care needs in the Netherlands.
Soc Sci Med
January 2025
Erasmus School of Health Policy & Management, Erasmus University Rotterdam, Postbus 1738, 3000 DR, Rotterdam, the Netherlands. Electronic address:
Fragmented care systems, characterized by horizontal and vertical boundaries, hinder interprofessional collaboration for individuals with complex care needs. This study explores how frontline professionals navigate these boundaries to foster collaboration within a national program promoting integrated care for individuals with 'misunderstood behaviour' in the Netherlands. Using a boundary work lens, we analysed 44 semi-structured interviews with frontline professionals from the social, care, and safety domains.
View Article and Find Full Text PDFWhat are the challenges that social prescribers face when supporting people within dementia and how can these be addressed? A qualitative study.
PLoS One
January 2025
Research Department of Primary Care & Population Health, Centre for Ageing Population Studies, University College London, London, United Kingdom.
Introduction: Evidence suggests that social prescribing might have a positive impact on identity, control, creativity and quality of life in people with dementia. While evidence on the benefits of social prescribing is accumulating, there is a sparsity of research on the experiences of social prescribers. This study aims to identify the challenges that social prescribers face when supporting people with dementia and their families and strategies to address these.
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