The Zika virus (ZIKV) genome, its negative-strand viral proteins, and virus-like particles were detected in placenta-derived mesenchymal cells (MSCs), indicating that ZIKV persists after virus clearance from maternal blood and can be rescued by in vitro cultivation. We report for the first time the presence of replication-competent ZIKV in MSCs from an asymptomatic woman who acquired infection during pregnancy.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6785694PMC
http://dx.doi.org/10.1093/ofid/ofz342DOI Listing

Publication Analysis

Top Keywords

replication-competent zikv
8
placenta-derived mesenchymal
8
mesenchymal cells
8
rescue replication-competent
4
zikv
4
zikv hidden
4
hidden placenta-derived
4
cells long
4
long resolution
4
resolution infection
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!