A new approach to the study of diseases of geochemical origin is presented, which is based on the hypothesis that all such geochemical endemias were not possible in conditions of virgin biosphere and are products of human civilization. Two genetically different types of endemic diseases of geochemical origin are distinguished, each having a specifically spatial structure: (1) diseases of natural origin due to natural element deficiency or excess in the particular zones or areas; (2) diseases of anthropogenic origin related to chemical transformation of the environment in the course of agricultural or industrial production. Anthropogenically provoked diseases of geochemical nature always occur in conditions of already formed natural geochemical heterogeneity. As each type of the endemic disease has a peculiar structure of spatial distribution, the present health risk can be mapped as a genetically two-layer structure, characterizing deviation of the existing geochemical conditions from those ideal for specific species. Parameters of geochemical conditions, which are ideal for humans and domesticated species, should be sought within the areas with undisturbed soil cover, where these species have been formed in their present form. The hypothesis is tested on example of thyroid diseases observed in iodine-deficient areas affected by a nuclear accident with I fallout. The developed approach is believed to serve as a practical tool for monitoring and prevention of endemic diseases of geochemical origin.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10653-019-00442-z | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Deciphering the mineral code of urinary stones: A first look at zinc isotopes.
Environ Pollut
December 2024
Nu Instruments, Wrexham Industrial Estate, 74 Clywedog Road South, Wrexham, LL13 9XS, United Kingdom.
Zinc (Zn) is an essential element for all living organisms, and Zn isotopes play a key role in studying the formation of disease. Despite extensive studies on Zn isotopes in healthy and diseased human tissues, the role of Zn isotopes in urinary stones remains unexplored. This study investigates Zn isotopes in 37 urinary stones using multi-collector inductively coupled plasma mass spectrometry.
View Article and Find Full Text PDFThe One Health concept, although formulated two decades ago, remains challenging to implement. It necessitates the integration of numerous scientific disciplines, diverse techniques and various professional expertise. Furthermore, it often requires the collaboration of different institutions, encompassing both scientific and administrative entities.
View Article and Find Full Text PDFHematological and immunological profiles of podoconiosis patients in West Gojjam Zone, Ethiopia: A comparative cross-sectional study.
PLoS Negl Trop Dis
December 2024
Department of Medical Laboratory Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Background: Podoconiosis is a geo-chemically induced, non-infectious, familial, chronic lymphedema of the legs that occurs among barefoot people in rural, farming communities with extreme poverty. Despite a growing body of research surrounding the disease, the pathogenesis of the disease is relatively unknown. This study aims to investigate the immunological and hematological profiles of individuals affected by podoconiosis in comparison to healthy controls.
View Article and Find Full Text PDFDelineating distinct sediment pollution signatures from diverse sources in a heavily contaminated estuary near an area of high cancer and cardiovascular mortality.
Sci Total Environ
December 2024
Department of Plant Biology and Ecology, University of Seville (US), Ap 1095, 41080 Seville, Spain.
Article Synopsis
- The study investigated pollution signatures in marsh sediments of the Odiel-Tinto Estuary to guide restoration efforts, focusing on various pollution sources like acid mine drainage and agricultural runoff.
- We analyzed chemical elements and sediment characteristics across multiple marshes, creating spatial maps to visualize pollution distributions from different sources.
- Our findings can help identify responsible polluters, assess the most affected areas, and serve as a baseline for evaluating the future impacts of the RESTORE 2030 restoration plan.
Detection of polyphenols in carob pods () from Southern Italy by a LC-HRMS method.
Nat Prod Res
November 2024
Dipartimento di scienze biomediche e biotecnologiche, Università degli studi di Catania, Catania, Italy.
Article Synopsis
- - The study analyzed the presence of polyphenols in carob pods from Southern Italy using a reliable LC-HRMS method, revealing high levels of Apigenin and Myricetin.
- - Significant variations in polyphenol content, especially in hesperidin and myricetin, were found between different sampling areas, indicating that geochemical and climatic factors influence these variations.
- - This research is the first to document the phenolic content of carob pods in this region after harvest and highlights their potential health benefits in preventing oxidative stress-related diseases.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!