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Construction and validation of a nomogram model to predict bronchiolitis Mycoplasma pneumoniae pneumonia in children.
Sci Rep
December 2024
Department of Pediatrics, the First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, 361003, China.
After the cancellation of COVID-19 epidemic control measures in 2023, cases of pediatric bronchiolitis caused by Mycoplasma pneumoniae (MP) have been reported successively, with some children experiencing residual bronchiolitis obliterans (BO). Currently, the diagnosis of bronchiolitis Mycoplasma pneumoniae pneumonia (MPP) primarily relies on high-resolution computed tomography (HRCT). To establish a predictive model for bronchiolitis MPP, a retrospective analysis was conducted.
View Article and Find Full Text PDFPets and related allergens modify the association between early life DEHP exposure and respiratory outcomes in children.
Environ Res
December 2024
University of Toronto, Toronto, ON, Canada; The Hospital for Sick Children, Toronto, ON, Canada. Electronic address:
Introduction: Throughout the perinatal period children are exposed to complex mixtures, including indoor chemicals such as phthalates, and biological agents. However, few studies focus on interactions between early-life co-exposures to shed light on how co-exposures modify their individual effects. Therefore, our study aims to assess whether early-life exposure to pets and related biological agents, namely pet allergens and endotoxin, modifies the association between di-(2-ethylhexyl) phthalate (DEHP) and asthma and wheeze in preschoolers to gain insight into interactions.
View Article and Find Full Text PDFResidential greenness and pollen exposure across gestational trimesters in relation to preschool wheezing: Results for the PIPO birth cohort.
Environ Res
December 2024
Social Epidemiology and Health Policy, Department of Family Medicine and Population Health, University of Antwerp, Doornstraat 331, BE-2610, Wilrijk, Belgium; Institute for Environment and Sustainable Development (IMDO), Groenenborgerlaan 171, BE-2020, Antwerpen, Belgium; Laboratory of Applied Microbiology and Biotechnology (LAMB), Department of Bioscience Engineering, University of Antwerp, Groenenborgerlaan 171, BE-2020, Antwerpen, Belgium.
Introduction: Previous studies on prenatal green space exposure and early respiratory health show inconsistent results. This may reflect stage-specific in utero effects and pollen influence. We examine associations of surrounding greenness and pollen exposure during pregnancy (overall and by trimester) with preschool wheezing, and assess potential mediation by pollen.
View Article and Find Full Text PDFEpidemiology of asthma across the ages.
Ann Allergy Asthma Immunol
December 2024
Allergy Department, 2nd Pediatric Clinic, National and Kapodistrian University of Athens, Athens, Greece; Lydia Becker Institute, University of Manchester, Manchester, UK. Electronic address:
In the last three decades, the overall prevalence of asthma appears to be plateauing, although large geographical and socioeconomic variation is evident. Overall, asthma prevalence slightly decreased in most age groups, except for school-aged children. Of note, asthma mortality steadily decreased, potentially highlighting improved asthma management strategies.
View Article and Find Full Text PDFAssociation of multiple environmental exposures with rhinitis and asthma symptoms in preschool children: Identifying critical risk factor.
Ecotoxicol Environ Saf
December 2024
Department of Environmental Health, School of Public Health, NHC Key Laboratory of Health Technology Assessment, Key Laboratory of Public Health Safety of the Ministry of Education, Fudan University, Shanghai 200032, China; Typhoon Institute/CMA, Shanghai Key Laboratory of Meteorology and Health, IRDR International Center of Excellence on Risk Interconnectivity and Governance on Weather/Climate Extremes Impact and Public Health WMO/IGAC MAP-AQ Asian Office Shanghai, Fudan University, Shanghai, China. Electronic address:
Background: The concept "one airway, one disease" for childhood rhinitis and asthma has been challenged in recent years. This study aimed to evaluate associations of environmental exposures with alone and co-morbid symptoms of rhinitis and asthma and identify critical risk factor.
Methods: 5828 children aged 3-6 years in Shanghai were surveyed in 2019.
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