A case report of photodermatoses induced by the antifungal drug terbinafine.

Eur J Hosp Pharm

Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail) - UMR_S 1085, Univ Rennes, CHU Rennes, F-35000 Rennes, France.

Published: September 2019

Terbinafine is an antifungaldrug(inhibitor of ergosterol synthesis) known to induce skin reactions. A 58-year-old female was treated with terbinafine for onychomycosis. On the fifth day of treatment a skin rash emerged on her sun-exposed areas. Biological testing did not find any allergic signs. Other skin reactions are well known with terbinafine, but we depict here, a case of photosensitisation induced by treatment, generally unknown for this antifungal. This side effect can be prevented by medication reconciliation and pharmaceutical advice from the clinical pharmacist.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788264PMC
http://dx.doi.org/10.1136/ejhpharm-2018-001683DOI Listing

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