Pseudopheochromocytoma manifests as severe, symptomatic paroxysmal hypertension without significant elevation in catecholamine and metanephrine levels and lack of evidence of tumor in the adrenal gland. The clinical manifestations are similar but not identical to those in excess circulating catecholamines. The underlying symptomatic mechanism includes augmented cardiovascular responsiveness to catecholamines alongside heightened sympathetic nervous stimulation. The psychological characteristics are probably attributed to the component of repressed emotions related to a past traumatic episode or repressive coping style. Successful management can be achieved by strong collaboration between a hypertension specialist and a psychiatrist or psychologist with expertise in cognitive-behavioral panic management.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6903402 | PMC |
| http://dx.doi.org/10.1016/j.ecl.2019.08.004 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A puzzling malignant adrenal tumor.
Ann Endocrinol (Paris)
December 2024
Department of Endocrinology, Santo António Local Health Unit, Largo Professor Abel Salazar, 4099-001 Porto, Portugal.
A previously healthy 49-year-old male presented with abdominal pain, constitutional syndrome, paroxysmal palpitations and diaphoresis. Full-body CT scan showed a large malignant adrenal mass with abdominal lymph node and pulmonary metastasis. Biochemical studies revealed hypersecretion of catecholamines, cortisol, sexual steroids and steroid precursors; ACTH was not suppressed, and chromogranin A was negative.
View Article and Find Full Text PDFLevodopa-Induced Pseudopheochromocytoma.
Eur J Case Rep Intern Med
May 2023
Hospital da Horta, Azores, Portugal.
Unlabelled: Pseudopheochromocytoma is a pathological condition presenting with paroxysmal hypertension with normal or moderate elevation in catecholamines and metanephrine levels, but no evidence of a tumoural cause. Imaging studies and I-123 metaiodobenzylguanidine scintigraphy are essential for exclusion of pheocromocytoma. We describe a case of pseudopheochromocytoma related to levodopa in a patient with paroxysmal hypertension, headache, sweating, palpitations and increased plasmatic and urinary metanephrine levels, without adrenal or extra-adrenal tumour.
View Article and Find Full Text PDFIatrogenic pseudopheochromocytoma.
Ann Endocrinol (Paris)
May 2023
Department of Endocrinology, University Hospital of Rouen, 1, rue de Germont, 76031 Rouen, France. Electronic address:
Clarifying the Cause and Treatment of Paroxysmal Hypertension (Pseudopheochromocytoma).
Curr Hypertens Rep
September 2022
Division of Nephrology and Hypertension, Kidney Health Research Institute, Geisinger Medical Center, 100 N Academy Avenue, Danville, PA, 17822, USA.
Purpose Of Review: To review the clinical characteristics of paroxysmal hypertension (pseudopheochromocytoma), its previously unsuspected cause, and effective treatment approaches.
Recent Findings: Patients with paroxysmal hypertension experience recurrent, sudden, unprovoked, symptomatic, and severe elevations of blood pressure that occur independently of current stress or perceived emotional distress. Recent findings point to a previously unsuspected psychosomatic etiology, linked in most to a past history of abuse, trauma, or prolonged severe stress, often with repression of pertinent emotions, or to a repressive coping style.
Vagus Nerve Stimulation-Induced Pseudo-Pheochromocytoma.
Neuromodulation
April 2022
Department of Neurology, Ghent University Hospital, Ghent, Belgium.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!