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http://dx.doi.org/10.1177/0025802419884748 | DOI Listing |
Diabetes Care
January 2025
Department of Epidemiology and Biostatistics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Objective: To estimate the incidence and identify risk factors for diagnosed type 2 diabetes (T2D) among young U.S. adults.
View Article and Find Full Text PDFPLoS One
January 2025
Department of Nutrition and Food Science, School of Arts and Sciences, Lebanese American University, Byblos, Lebanon.
University students are at a pivotal stage of shaping cancer risk factors. Little is known about their dietary behavior in Lebanon, a country heavily burdened by cancer. This cross-sectional study assessed the dietary knowledge of and adherence to cancer prevention guidelines among university students in Beirut, Lebanon.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Departments of Psychiatry and Behavioral Sciences, Neurology, and Epidemiology, University of California San Francisco, San Francisco, CA, USA.
Background: Integrating clinical and genetic risk factors for dementia in a precision medicine framework can play a crucial role in primary prevention. Here, we ascertained the proportion of individuals who are at heightened risk of developing dementia based on their family history, genetic, and clinical risk factors and evaluated how the additive burden of these risk indicators is associated with incident dementia.
Method: We analyzed longitudinal data from 3,395 diverse older adults, dementia-free at baseline with follow-up and whole genome sequencing, enrolled in the National Alzheimer's Co-coordinating Center and the Alzheimer's Disease Neuroimaging Initiative (Table 1).
Alzheimers Dement
December 2024
Albany Medical College, Albany, NY, USA.
Background: About two-thirds of those with Alzheimer's disease (AD) are women, most of whom are post-menopausal. Menopause accelerates the risk for dementia by increasing the risk for metabolic, cardiovascular, and cerebrovascular diseases. Mid-life metabolic disease (e.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, NV, USA.
Background: Women are at increased risk for Alzheimer's disease (AD) compared to men. Given research supporting up to 40% of AD cases as preventable with lifestyle modification, midlife represents a critical time of life to intervene on dementia risks; however, little research has examined women-specific presentation of risk at midlife, or how menopause staging may impact risk presentation. The aim of this study was to assess dementia risk profiles in women at risk for AD due to family history, including self-reported and lab-based modifiable risks, and to determine the role of menopause on risk presentation.
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