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The relationship between mean platelet volume and platelet levels of children with and gastritis. | LitMetric

AI Article Synopsis

  • The study investigated the relationship between Helicobacter pylori (HP) positivity, gastritis, mean platelet volume (MPV), and platelet levels in patients with dyspeptic complaints.
  • A total of 309 patients were analyzed, revealing that 64% tested positive for HP, but no significant differences in MPV values were found between HP positive and negative cases.
  • The findings suggest only a weak link exists between HP and platelet values, with no significant correlation between gastritis severity and MPV.

Article Abstract

Introduction: (HP) is an infectious agent worldwide and is detected frequently.

Aim: We examined whether there is a relationship between HP positivity and gastritis, mean platelet volume (MPV), and platelet level.

Material And Methods: A total of 309 patients who presented to the Paediatric Gastroenterology Polyclinic with dyspeptic complaints, who received upper gastrointestinal endoscopy, and whose gastric biopsies were carried out were included in the present study. MPVs, thrombocyte, presence of HP, and histopathological presence of gastritis in the patients were examined. The MPV and thrombocyte values were compared between the patients who were HP positive and negative, and between the cases who had and who did not have gastritis.

Results: A total of 36% of the cases who were included in the present study were HP(-), and 64% were HP(+). No gastritis was detected in 22% of the cases. No significant differences were detected between the HP(+) and HP(-) cases in terms of MPV values. The platelet values were determined to be low at a significant level in the HP(+) group, although no significant differences were detected between all the cases who had and who did not have gastritis in terms of MPV.

Conclusions: A weak relation was determined between the HP and MPV and platelet values. Although no relations were detected between the presence of gastritis or its severity and MPV, a weak relation was detected between the presence of gastritis and platelet values.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6807664PMC
http://dx.doi.org/10.5114/pg.2019.88169DOI Listing

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