Internal Working Models of the attachment system modulate emotional responses and the Disorganized attachment pattern is characterized by the breakdown of such regulation. Vagally-mediated heart rate variability (vmHRV) is an index of flexible emotional responding. This study investigated vmHRV in non-clinical adults with an Organized or Disorganized attachment pattern before, during, and after the recall of attachment memories via the Adult Attachment Interview (AAI). Whereas the Organized group exhibited a typical decrease in vmHRV during the AAI and asubsequent return to a baseline-like pattern, the Disorganized group unexpectedly showed a sustained increase in vmHRV during the AAI which also persisted during the recovery phase. Results suggest that while Organized face the recollection of attachment memories by showing the adaptive stress response characterized by parasympathetic withdrawal and immediate recovery, individuals with Disorganized attachment need to keep regulating their emotions effortfully both during and after the recall of potential traumatic events.
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http://dx.doi.org/10.1080/14616734.2019.1680712 | DOI Listing |
Eur J Neurosci
January 2025
Department of Philosophy, Radboud University, Nijmegen, The Netherlands.
Conceptual review is a method to address issues of task comparability and task validity in cognitive neuroscience. Meta-analyses within cognitive neuroscience (CNS) as well as integration of neuroscientific findings with findings from adjacent disciplines both involve gathering studies that have purportedly investigated the same mental concept. After all, it is no use comparing apples and oranges.
View Article and Find Full Text PDFAttach Hum Dev
January 2025
Department of Psychology, University of Regensburg, Regensburg, Germany.
Our memories reflect professional meetings and our private relationship with Mary Main for over more than 50 years, working, travelling jointly, and celebrating together. Klaus met Mary Main at Mary Ainsworth's lab in 1973 in Baltimore. Mary Main's and our own longitudinal studies both started at the same time in which attachment research became a focus of several research groups.
View Article and Find Full Text PDFComput Biol Med
January 2025
Thai Nguyen University of Information and Communication Technology, Thai Nguyen City, Viet Nam. Electronic address:
Protein succinylation, a post-translational modification wherein a succinyl group (-CO-CH₂-CH₂-CO-) attaches to lysine residues, plays a critical regulatory role in cellular processes. Dysregulated succinylation has been implicated in the onset and progression of various diseases, including liver, cardiac, pulmonary, and neurological disorders. However, identifying succinylation sites through experimental methods is often labor-intensive, costly, and technically challenging.
View Article and Find Full Text PDFInt J Mol Sci
December 2024
Department of Neurology, Davis School of Medicine, University of California, 1515 Newton Court, Davis, CA 95618, USA.
We have designed and produced 39 amino acid peptide mimics of the and human acetylcholine receptors' (AChRs) main immunogenic regions (MIRs). These conformationally sensitive regions consist of three non-contiguous segments of the AChR α-subunits and are the target of 50-70% of the anti-AChR autoantibodies (Abs) in human myasthenic serum and in the serum of rats with a model of that disease, experimental autoimmune myasthenia gravis (EAMG), induced by immunizing the rats with the electric organ AChR. These MIR segments covalently joined together bind a significant fraction of the monoclonal antibodies (mAbs) raised in rats against electric organ AChR.
View Article and Find Full Text PDFPhys Eng Sci Med
January 2025
RF Longevity, 428 E. Thunderbird Road, Phoenix, SE, AZ, 85022, USA.
We have previously shown in small studies that full brain Transcranial Radiofrequency Wave Treatment (TRFT) to subjects with Alzheimer's Disease could stop and reverse their cognitive decline. An 8-emitter head device, the "MemorEM", was used in these studies to provide TRFT at 915 MHz frequency and power level of 1.6 W/kg Specific Absorption Rate (SAR) during daily 1-hour treatments.
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