Tendinopathy of the mid-portion of the Achilles tendon is common in athletes and non-athletes. From a physiotherapeutic view, calf muscle training is the most recommended kind of treatment. However, there is no current systematic review evaluating the efficacy of physiotherapy in due consideration of the entire spectrum of therapeutic options. A systematic review of the literature in several databases and journals revealed 19 relevant studies. Good evidence was found for eccentric training compared to no therapy, satisfactory evidence for eccentric training compared to concentric training, satisfactory to good evidence for the same effect by using eccentric training and heavy slow resistance training, poor evidence for the same effect by using eccentric training and stretching, and poor to good evidence that eccentric training may have the same effect as several therapies applied by physicians. The Alfredson protocol and heavy slow resistance training may be the most recommendable types of calf muscle training. There is no high-quality evidence for the efficacy of other hands off or hands on treatment options.
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http://dx.doi.org/10.1055/a-0877-3407 | DOI Listing |
Nanoscale
January 2025
School of Materials and Chemistry, University of Shanghai for Science and Technology, 516 Jungong Road, Shanghai 200093, China.
Thermoplastic polyurethane (TPU) fabrics often possess good mechanical, waterproofing, and breathability properties. However, the resistance of TPU to excessive ultraviolet (UV) irradiation is poor and often does not meet the UV resistance requirements of fabrics. Electrospun nanofibers with a side-by-side structure can combine the advantages of different materials.
View Article and Find Full Text PDFActa Ophthalmol
January 2025
Harvard University, Boston, Cambridge, USA.
Purpose: There is evidence of the role of dark adaptation (DA) as a functional biomarker in age-related macular degeneration (AMD) where foveal cones are impacted during the initial stages of AMD. In this study we determine the repeatability of smartphone application (MOBILE DA) to evaluate the cone-mediated dark adaptation (DA) in healthy young adults.
Methods: Testing was done by placing a smartphone in front of the subject in a dark room.
J Shoulder Elbow Surg
January 2025
Palm Beach Shoulder Service HCA Florida Atlantis Orthopedics, Palm Beach, FL, USA; JFK/University of Miami Department of Orthopedics, Lake Worth, FL, USA. Electronic address:
Background: Glenoid bone loss presents a complex challenge in the management of patients with glenohumeral osteoarthritis (GHOA) undergoing Reverse Shoulder Arthroplasty (RSA). Eccentric reaming and bone grafting have been utilized to address this issue but are associated with their own set of challenges. This study explores the effectiveness of augmented glenoid baseplate RSA in addressing glenoid bone loss.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2025
Department of Cardiology, The Second Affiliated Hospital, Jiangxi Medical College, Nanchang University, No. 1 Minde Road, Nanchang, Jiangxi Province 330006, China. Electronic address:
Aims: Nanoplastics (NPs) are emerging organic pollutants generated by plastic degradation and are ubiquitous in the environment. They can be accumulated through the food webs and enter the human body through dietary intake, posing health risks. The main target organs of NP accumulation are the lungs, liver, heart, and kidneys.
View Article and Find Full Text PDFFASEB J
January 2025
Shirley Ryan AbilityLab, Chicago, Illinois, USA.
Following injury, skeletal muscle undergoes repair via satellite cell (SC)-mediated myogenic progression. In SCs, the circadian molecular clock gene, Bmal1, is necessary for appropriate myogenic progression and repair with evidence that muscle molecular clocks can also affect force production. Utilizing a mouse model allowing for inducible depletion of Bmal1 within SCs, we determined contractile function, SC myogenic progression and muscle damage and repair following eccentric contractile-induced injury.
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