AI Article Synopsis
- - Two iron(II) complexes, [(Tp)Fe(benzilate)] and [(Tp)(Fe)(NPP)], are studied for their ability to oxidize oximes in the presence of dioxygen, each following different mechanisms.
- - The first complex, [(Tp)Fe(benzilate)], interacts with dioxygen to produce HNO from oximes, while the second complex, [(Tp)(Fe)(NPP)], transforms oximes into NO.
- - The findings indicate that the oxidative transformation pathways to nitric oxide and nitroxyl depend on the type of co-ligand and reductant present in the reaction.
Article Abstract
The ability of two iron(II) complexes, [(Tp)Fe(benzilate)] (1) and [(Tp)(Fe)(NPP)] (2) (Tp = hydrotris(3,5-diphenylpyrazol-1-yl)borate, NPP-H = α-isonitrosopropiophenone), of a monoanionic facial N3 ligand in the O-dependent oxidation of oximes is reported. The mononuclear complex 1 reacts with dioxygen to decarboxylate the iron-coordinated benzilate. The oximate-bridged dinuclear complex (2), which contains a high-spin (Tp)Fe unit and a low-spin iron(II)-oximate unit, activates dioxygen at the high-spin iron(II) center. Both the complexes exhibit the oxidative transformation of oximes to the corresponding carbonyl compounds with the incorporation of one oxygen atom from dioxygen. In the oxidation process, the oxime units are converted to nitric oxide (NO) or nitroxyl (HNO). The iron(II)-benzilate complex (1) reacts with oximes to afford HNO, whereas the iron(II)-oximate complex (2) generates NO. The results described here suggest that the oxidative transformation of oximes to NO/HNO follows different pathways depending upon the nature of co-ligand/reductant.Graphic abstract.
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