Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/s0022-3476(88)80235-x | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Gold nanoparticles "AuNPs" -mediated amelioration of experimentally toxic-induced cerebellar syndrome: Insights into cytomolecular and immuno-histochemical modifications, with a focus on CREB/ Tau modulation.
Tissue Cell
January 2025
Human Anatomy & Embryology Department, Faculty of Medicine, Zagazig University, Egypt.
Toxic-induced cerebellar syndrome (TOICS) poses substantial neurological challenges, given its diverse causes and complex manifestations. Gold nanoparticles (AuNPs) have gained significant attention owing to enhanced biocompatibility for therapeutic interventions. We aimed to investigate the impacts of AuNPs on cerebellar cytomolecular, immunohistochemical and ultrastructural alterations in the context of phenytoin-experimentally induced TOICS.
View Article and Find Full Text PDFEffect of antiepileptic drug monotherapy on endogenous sex hormonal profile in men and women with epilepsy.
Epilepsy Behav
December 2024
Council of Scientific and Industrial Research -Institute of Genomics and Integrative Biology (CSIR-IGIB), Delhi 110007, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address:
Objective: To assess the alterations of endogenous sex hormone profiles in patients with epilepsy (PWE) on different antiepileptic drug (AED) monotherapies compared to healthy controls and drug naïve PWE (DNPWE).
Methods: Four databases MEDLINE, EMBASE, SCOPUS, and CENTRAL were searched for analytical observational/intervention studies on the assessment of endogenous sex hormones in PWE compared to healthy controls and DNPWE. Two researchers reviewed the title/abstract, and full-text articles for the selection of the studies independently.
Shape analysis of the craniofacial skeleton in children prenatally exposed to anticonvulsant medications using geometric morphometrics.
J Anat
February 2025
Department of Orthodontics and Dentofacial Orthopedics, Boston University Henry M. Goldman School of Dental Medicine, Boston, Massachusetts, USA.
Children exposed prenatally to antiepileptic drugs may have a typical facies characterized by midfacial retrusion, a short nose, and anteverted nares. Our aim was to determine whether the shape of the maxilla was altered in its sagittal displacement, or whether the defect in the underlying articulation with the cranial base was responsible for the appearance of midface retrusion. Our hypothesis was that the sphenoid bone as well as the maxilla and other bones in the cranial base were affected by the anticonvulsant medication.
View Article and Find Full Text PDFAccidental Intrathecal Tranexamic Acid Injection During Caesarean Section: A Case Report.
Case Rep Anesthesiol
October 2024
Department of Obstetrics and Gynaecology, Muhimbili National Hospital, Dar es Salaam, Tanzania.
Tranexamic acid (TXA) is increasingly used in the management of haemorrhage during and after delivery and haemorrhage caused by other medical conditions due to its efficacy and safety. However, increasing report of fatal complications from inadvertent intrathecal TXA injection remains a cause of concern. The aim of this case report is to demonstrate clinical presentation and predictors of accidental intrathecal injection of TXA within the structure and processes of care in a health facility.
View Article and Find Full Text PDFAdvances in serum thyroid hormone levels and seizures.
Epilepsy Behav
November 2024
The Affiliated Lianyungang Hospital of Xuzhou Medical University, China. Electronic address:
Article Synopsis
- Epilepsy is a neurological disorder that affects quality of life and involves changes in brain activity, neurotransmitter imbalances, and GABA receptor dysfunction, with its causes still not fully understood.
- Thyroid hormones are important for brain function and can influence seizure activity by regulating oxidative stress and neurotransmitter levels, so defects in their signaling may lead to more frequent seizures and neurodevelopmental disorders.
- Traditional antiseizure medications may disrupt thyroid hormone levels, with some, like phenobarbital and carbamazepine, potentially causing hypothyroidism, while newer medications like levetiracetam don’t impact thyroid levels, highlighting the complex interplay between seizures and thyroid hormone dynamics.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!