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Treatment, prognosis, and outcome of dogs treated for rectal plasmacytoma: a multicentric retrospective study.
J Am Vet Med Assoc
January 2025
7Royal Veterinary College, University of London, Hatfield, UK.
Objective: The aim of this study was to report the outcome and prognosis of canine patients treated medically or surgically for rectal plasmacytomas and to identify factors associated with recurrence, mortality, or progression to multiple myeloma.
Methods: The databases of 7 referral hospitals were reviewed. The Kaplan-Meier method and Cox proportional hazards analysis were used to determine the association of a range of variables with recurrence and progression-free interval for the surgically treated patients.
Cracking the code: lncRNA-miRNA-mRNA integrated network analysis unveiling lncRNAs as promising non-invasive NAFLD biomarkers toward precision diagnosis.
Comput Biol Chem
January 2025
Institute of Global Health and Human Ecology (IGHHE), School of Sciences and Engineering, The American University in Cairo, New Cairo 11835, Egypt. Electronic address:
Background: Non-alcoholic fatty liver disease (NAFLD) involves abnormal fat accumulation in the liver, mainly as triglycerides. It ranges from steatosis to non-alcoholic steatohepatitis (NASH), which can lead to inflammation, cellular damage, liver fibrosis, cirrhosis, or hepatocellular carcinoma (HCC). Long non-coding RNAs (lncRNAs) are crucial for regulating gene expression across various conditions.
View Article and Find Full Text PDFExtramedullary plasmacytoma is rare, it can appear alone or associated with multiple myeloma, representing an extramedullary progression of the disease. We present the case of a 62-year-old woman diagnosed with multiple myeloma who, being in complete remission began to experience abdominal pain and nausea. A rare cause of intestinal subocclusion and upper gastrointestinal bleeding.
View Article and Find Full Text PDFCutaneous Plasmacytosis: A Rare Dermatological Condition Mimicking Systemic Plasma Cell Disorders.
Cureus
December 2024
Dermatology, Marshall University Joan C. Edwards School of Medicine, Huntington, USA.
Cutaneous plasmacytosis (CP) is a rare condition characterized by benign proliferation of mature plasma cells in the skin. It presents as reddish-brown macules, papules, or plaques, typically located on the neck, face, and trunk. The etiology remains unknown, though it is believed to be reactive rather than malignant.
View Article and Find Full Text PDFSolitary plasmacytoma: an unusual presentation.
BMJ Case Rep
January 2025
Radiology Department, Port of Spain General Hospital, Port of Spain, Trinidad and Tobago.
This case highlights the importance of thoroughly investigating incidental findings, particularly in patients with unexplained symptoms. Solitary plasmacytoma, though rare and accounting for 4-5% of plasma cell dyscrasias, can occur outside the spine and may present without systemic symptoms. Early diagnosis through imaging and biopsy is crucial for appropriate management, as these lesions can be effectively treated if identified early.
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