Pathology of Rotavirus-driven Multiple Organ Failure in a 16-month-old Boy.

Pediatr Infect Dis J

From the National Reference Centre for Gastroenteritis Viruses, Laboratory of Virology, University Hospital of Dijon Bourgogne, Dijon, France.

Published: December 2019

Autopsy investigation of a fatal case of rotavirus severe acute gastroenteritis and multiple organ failure in a 16-month boy with previous intrauterine growth retardation showed colocalization of nonstructural and structural rotavirus proteins within viroplasms in nephrons. This case brings new insights into extraintestinal rotavirus infection and new clues to its abilities to bind to human histo-blood group antigens.

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Source
http://dx.doi.org/10.1097/INF.0000000000002472DOI Listing

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