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| http://dx.doi.org/10.1002/cld.829 | DOI Listing |
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Metabolic dysfunction-associated steatotic liver disease and extrahepatic gastrointestinal cancers.
Metabolism
November 2024
Department of Medicine, University of Verona, Italy; Metabolic Diseases Research Unit, IRCCS Sacro Cuore - Don Calabria Hospital, Negrar di Valpolicella, Italy. Electronic address:
Article Synopsis
- - Metabolic dysfunction-associated steatotic liver disease (MASLD) is an increasingly common condition that significantly impacts health by raising risks for liver complications, cardiometabolic issues, and gastrointestinal (GI) cancers, which are a major contributor to cancer deaths globally.
- - The review explores evidence linking MASLD to non-liver GI cancers, examining factors that may explain this increased risk and highlighting the need for tailored screening for individuals with MASLD.
- - Potential treatments like aspirin, statins, and metformin may help reduce the risk of GI cancers associated with MASLD, but more research is needed to solidify these findings.
Comparative analysis of Sarcopenia in hospitalized elderly: exploring the impact of liver cirrhosis.
Intern Emerg Med
October 2024
Internal Medicine and Liver Unit, Department of Medical and Surgical Sciences, University of Foggia, Policlinico Riuniti, 71122, Foggia, Italy.
The progressive aging of the population has led to a rise in geriatric pathologies, with sarcopenia, characterized by muscle mass and function loss, becoming a crucial prognostic indicator. This study investigates sarcopenia in elderly hospitalized patients with advanced chronic liver disease (cirrhotic) and non-liver disease patients, comparing their prevalence and exploring correlations with anthropometric and biochemical factors. The cohort of 115 patients, including 50 cirrhotic and 65 non-cirrhotic individuals, exhibited significant comorbidities and a mean age of 78.
View Article and Find Full Text PDFEffective and Safe Treatment of Risky Localized Liver Tumors Using Microwave Ablation in Patients with Comorbid Lung Diseases Unfit for Deep Anesthesia.
Medeni Med J
March 2024
Istanbul Medeniyet University Faculty of Medicine, Department of Radiology, Istanbul, Turkey.
Objective: To assess the safety and efficacy of percutaneous microwave ablation (MWA) in treating high-risk localized liver tumors in patients unable to undergo deep anesthesia because of comorbid lung diseases.
Methods: Between January 2019 and January 2022, percutaneous MWA procedures were performed for 50 liver tumors. These lesions were situated in close proximity to anatomically essential structures, with a maximum distance to surrounding structures being 10 mm.
Global incidence of adverse clinical events in non-alcoholic fatty liver disease: A systematic review and meta-analysis.
Clin Mol Hepatol
April 2024
Division of Gastroenterology and Hepatology, Stanford University Medical Center, Palo Alto, CA, USA.
Background/aims: Nonalcoholic fatty liver disease (NAFLD) is associated with a multitude of adverse outcomes. We aimed to estimate the pooled incidence of NAFLD-related adverse events.
Methods: We performed a systematic review and meta-analysis of cohort studies of adults with NAFLD to evaluate the pooled incidence of adverse events.
Differential Mortality Outcomes in Real-world Patients with Lean, Nonobese, and Obese Nonalcoholic Fatty Liver Disease.
J Clin Transl Hepatol
December 2023
Division of Gastroenterology and Hepatology, Stanford University Medical Center, Palo Alto, CA, USA.
Background And Aims: Nonalcoholic fatty liver disease (NAFLD) is commonly associated with obesity but can develop in normal-weight people (lean NAFLD). We compared outcomes in lean, overweight, and obese NAFLD.
Methods: This retrospective chart review included patients at Stanford University Medical Center with NAFLD confirmed by imaging between March 1995 and December 2021.
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