Objective: To determine the association between daily particulate matter 2.5 (PM ) mass and emergency calls for help with respiratory diseases.

Methods: Semi-parametric generalized additive model was established to determine the association between daily PM and emergency calls for help with respiratory diseases in 2017 in Chengdu, after adjustments for time trend and variations in the days of the week and weather conditions.

Results: In 2017, a total of 9 309 emergency calls for help with respiratory diseases were recorded in Chengdu: on average 26 calls a day. Over the year, Chengdu reported a mean PM mass concentration of 53.6 μg/m , an average temperature of 16.6 ℃, and an average relative humidity of 81.2%. The single pollutant model with lag time effect showed that a 10 μg/m increase in PM was associated with an increase of 1.26% (95% confidence interval ( ) 0.56%-1.97%) emergency calls for help with respiratory diseases. The exposure-response was almost in a direct line. The dual pollutant model found that O 8-hour sliding average (O ) enhanced the effect of PM on emergency calls for help with respiratory diseases.

Conclusion: Outdoor PM is a significant predictor of emergency calls for help with respiratory diseases in Chengdu.

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