Purpose: We designed and implemented an orthogonal shim array consisting of shim coils with their planes perpendicular to the planes of neighboring RF coils. This shim coil improves the magnetic field homogeneity by minimizing the interference to RF coils.
Methods: Using realistic off-resonance maps of the human brain, we first evaluated the performance of shim coils in different orientations. Based on simulations, we developed a 7-channel orthogonal shim array, whose coil plan was perpendicular to neighboring RF coils, at the forehead. A programmable open-source current driver supplied shim currents.
Results: The 7-channel orthogonal shim array caused only marginal SNR loss to the integrated 32-channel RF-shim array. The 7-channel orthogonal shim array itself improved the magnetic field homogeneity by 30% in slice-optimized shimming, comparable to the baseline shimming offered by the scanner's 2nd order spherical harmonic shimming.
Conclusion: Orthogonal shim coils can improve the field homogeneity while maintaining high image SNR.
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http://dx.doi.org/10.1002/mrm.28010 | DOI Listing |
Magn Reson Med
March 2025
UT Southwestern Medical Center, Dallas, Texas, USA.
Sci Rep
October 2023
Institute of Microstructure Technology (IMT), Karlsruhe Institute of Technology (KIT), Eggenstein-Leopoldshafen, 76344, Karlsruhe, Germany.
Rapid drug development requires a high throughput screening technology. NMR could benefit from parallel detection but is hampered by technical obstacles. Detection sites must be magnetically shimmed to ppb uniformity, which for parallel detection is precluded by commercial shimming technology.
View Article and Find Full Text PDFMagn Reson Med
December 2023
Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Purpose: Developing a general framework with a novel stochastic offset strategy for the design of optimized RF pulses and time-varying spatially non-linear ΔB shim array fields for restricted slice excitation and refocusing with refined magnetization profiles within the intervals of the fixed voxels.
Methods: Our framework uses the decomposition property of the Bloch equations to enable joint design of RF-pulses and shim array fields for restricted slice excitation and refocusing with auto-differentiation optimization. Bloch simulations are performed independently on orthogonal basis vectors, Mx, My, and Mz, which enables designs for arbitrary initial magnetizations.
Nanophotonics
June 2023
Department of Physics, University of Ulsan, Ulsan 44610, Republic of Korea.
Anisotropic materials with chirality or birefringence can be used to manipulate the polarization states of electromagnetic waves. However, the comparatively low anisotropy of natural materials hinders the miniaturization of optical components and devices at terahertz frequencies. In this study, we experimentally demonstrate that the relative phase retardation of a THz wave can be electrically controlled by integrating patterned mono- and bilayer graphene onto an otherwise isotropic metasurface.
View Article and Find Full Text PDFNanomaterials (Basel)
September 2022
KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Korea.
Gold nanoparticles (AuNPs) with various sizes and morphologies have been extensively investigated for effective photothermal therapy (PTT) against multiple cancer types. However, a highly dynamic and complex tumor microenvironment (TME) considerably reduces the efficacy of PTT by limiting deep tumor penetration of AuNPs. Herein, we propose a mesenchymal stem cell (MSC)-mediated deep tumor delivery of gold nanorod (AuNR) for a potent PTT.
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