[Comparative study of prolactin-secreting and hormonally inactive pituitary adenomas in patients with moderate hyperprolactinemia].

The present paper deals with the differential prolactin diagnosis of pituitary adenomas with moderate prolactin hyperproduction and hormonally inactive pituitary adenomas. Sixty patients with gross pituitary adenomas were examined. Morphological analysis of in-traoperative samples included histological, immunohistochemical studies with antibodies to hormones of the adenohypophysis. There was a probable frequency of prolactin-secreting tumors among gross pituitary adenomas proceeding with moderate hyperprolactinemia (25%) and that of hormonally inactive pituitary adenomas among the tumors regarded as prolactinomas (16%) in the preoperative period.