Objective: The aim of this study was to evaluate the consequences of different oxygen supplementation methods on arterial blood gas analysis during an injectable anesthesia.
Material And Methods: A total of 29 rabbits with dental diseases (tooth elongation) were sampled before, during and after coronal reduction. Oxygen was provided either via the flow-by method or with a nasal oxygen tube; the control group breathed room air.
Results: All patients receiving oxygen developed respiratory acidosis that intensified during the course of anesthesia. Furthermore, these groups experienced reduced respiratory rates intraoperatively, nevertheless they showed elevated oxygen parameters (hyperoxemia) in the arterial blood gas analysis. No significant differences could be demonstrated between the 2 oxygen providing methods. In the control group, pH remained stable, the oxygen parameters however decreased to less than 80 mmHg (hypoxemia).
Conclusions: Although there were no clinical consequences of hypoxemia or hyperoxemia, moderate oxygen support during an injectable anesthesia is recommended due to the development of hypoxemia. A balance between oxygen supply and oversupply needs to be established to aid in avoiding oxygen toxicity.
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http://dx.doi.org/10.1055/a-1002-0327 | DOI Listing |
Retina
January 2025
National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou, 325027, China.
Purpose: Anterior chamber air injection (ACAI) is a surgical technique used to decrease the occurrence of postoperative intraocular lens (IOL) haptic dislocation following phacovitrectomy with gas/air tamponade. The impact of this technique on IOL stability remains uncertain, prompting the design of this study to investigate further.
Methods: This study included 51 eyes of 51 patients who underwent phacovitrectomy with gas/air tamponade.
Am J Respir Cell Mol Biol
January 2025
Rostock University Medical Center, Institute of Medical Microbiology, Virology and Hygiene, Rostock, Germany.
(Group A Streptococcus, GAS) is a human pathogen that causes local and systemic infections of the skin and mucous membranes. However, GAS is also found asymptomatically in the nasopharynx of infants. GAS infections, including pharyngitis and invasive pneumosepsis, pose significant public health concerns.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Nanomaterials Laboratory, Department of Polymers and Functional Materials, CSIR-Indian Institute of Chemical Technology, Uppal Road, Tarnaka, Hyderabad 500 007, India.
Herein, porous SnO microspheres in a three-dimensional (3D) hierarchical architecture were successfully synthesized via a facile hydrothermal route utilizing d-(+)-glucose and cetyltrimethylammonium bromide (CTAB), which act as reducing and structure-directing agents, respectively. Controlled adjustment of the CTAB to glucose mole ratio, reaction temperature, reaction time, and the calcination parameters all provided important clues toward optimizing the final morphologies of SnO with exceptional structural stability and reasonable monodispersity. Electron microscopy analysis revealed that microspheres formed were hierarchical self-assemblies of numerous primary SnO nanoparticles of ∼3-8 nm that coalesce together to form nearly monodispersed and ordered spherical structures of sizes in the range of 230-250 nm and are appreciably porous.
View Article and Find Full Text PDFRetin Cases Brief Rep
January 2025
Chair of Ophthalmology division; Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv, Israel.
Purpose: To evaluate the potency and security of Pneumatic Vitreolysis (PVL) as the primary treatment for Full-Thickness Macular Holes (FTMHs) and provide insights into patient selection criteria and procedural outcomes.
Patients And Methods: A retrospective analysis of three clinical cases presenting with FTMHs treated initially with PVL was conducted. Cases were evaluated for anatomical and functional outcomes through comprehensive ophthalmic examination and optical coherence tomography (OCT) imaging.
Appl Biochem Biotechnol
January 2025
Tissue Culture and Drug Discovery Laboratory, Department of Biotechnology, Anna University, Chennai, 600 025, India.
Multi-targeted therapies are gaining attention in the management of multifactorial diseases due to their poly pharmacology, enhanced potency and reduced toxicity. Metabolic disorders like Type 2 diabetes mellitus (T2DM) and obesity necessitate multi-targeted therapy to improve insulin sensitivity, regulate glucose homeostasis and support weight loss. Medicinal plants rich in bioactive compounds exhibit multi-targetted action with minimal side effects.
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