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| http://dx.doi.org/10.1016/j.bjid.2019.09.002 | DOI Listing |
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What's Eating You? Hookworm and Cutaneous Larva Migrans.
Cutis
November 2024
Dr. Bloomquist is from the School of Medicine, University of South Carolina, Columbia. Dr. Elston is from the Department of Dermatology & Dermatologic Surgery, Medical University of South Carolina, Charleston.
Hookworm infection represents a major global disease burden, in terms of both morbidity and economic impact, and there has been a resurgence of hookworms in developed nations where these parasites were once thought to be eradicated. Hookworms can infest humans or other mammals as their primary hosts depending on the species. The 2 most common species that seek human hosts-Necator americanus and Ancylostoma duodenale-enter the body through the epidermis, and hookworm infection may manifest as a pruritic and papular inflammatory reaction know as ground itch.
View Article and Find Full Text PDFChallenges in establishing small animal models for : Host specificity and resistance to infection in rodent hosts.
MicroPubl Biol
December 2024
Microbiology, Immunology, and Tropical Medicine, George Washington University, Washington, Washington, D.C., United States.
This study explores potential small animal models for the dog hookworm, , a parasitic nematode which has repeatedly exhibited the ability to develop resistance to a range of anthelmintics. Immunomodulated hamsters, gerbils, rats, and mice were infected with Despite varying degrees of immunosuppression, and in some cases, total adaptive immunodeficiency, no adult worms were recovered, and larval arrest (L3 stage) occurred in muscle tissue of mice and hamsters. This highlights the strict host specificity of and emphasizes the challenges of developing rodent models usable for anthelmintic testing with a strict specialist parasite.
View Article and Find Full Text PDFIdentification of Ancylostoma caninum in Domestic Dogs from Ecuador via Various Techniques.
Med Sci Monit
January 2025
Institute of Invertebrates, Fundación Miguel Lillo, San Miguel de Tucumán, Argentina.
BACKGROUND Ancylostoma caninum is a soil-borne, soil-transmitted helminth with infective larvae and produces cutaneous larva migrans in humans. The objective of this study was to confirm the presence of A. caninum in domestic dogs from the urban-marginal and rural sectors of the Ecuadorian coast through morphometry, culture, and molecular techniques.
View Article and Find Full Text PDFTriple soil transmitted helminths in a case of aluminium phosphide poisoning.
Indian J Med Microbiol
January 2025
Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. Electronic address:
Soil transmitted helminth (STH) infections remain prevalent in India despite the ongoing deworming program. Here, we report a case of triple infection of Ascaris lumbricoides, Ancylostoma duodenale, and Strongyloides stercoralis, in a young asymptomatic and apparently immunocompetent female presenting with aluminium phosphide poisoning. Except for severe anaemia, the only other indicators of chronic infection were occasional abdominal pain and self-limiting loose stools.
View Article and Find Full Text PDFEvaluation of a 70 kDa Excreted/Secreted Coproantigen Immunoassay for the Detection of in Dogs.
Iran J Parasitol
January 2024
Department of Invertebrates Zoology, Biological Sciences School, Autonomous University of Nuevo León, San Nicolás de los Garza, Nuevo León, México.
Background: We aimed to develop a sandwich ELISA, using polyclonal antibodies against excretory/secretory (E/S) antigens specific to coproantigens present in -positive dogs.
Methods: Antibodies were produced at Biological Sciences School, Autonomous University of Nuevo León, in 2023 by immunization of rabbits with antigenic extracts from in vitro cultures of larvae. Assays were performed on 100 stool samples from pet dogs, measuring sensitivity, specificity, and cross-reactivity against other parasitic infections.
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