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Reconceptualizing Disorders of the Self as Disorders of Relationship.
Arch Phys Med Rehabil
January 2025
Objective: To validate a universal neuropsychological model that suggests that disorders of the self are best conceptualized as disintegrated neuropsychological processes (i.e., sensations, mental experiences) that lack a sense of relationship to the unified experience/sense of self.
View Article and Find Full Text PDFAn ensemble learning method combined with multiple feature representation strategies to predict lncRNA subcellular localizations.
Comput Biol Chem
January 2025
School of Mechanical, Electrical and Information Engineering, Shandong University at Weihai, 264209, China. Electronic address:
Long non-coding RNAs (lncRNAs) are strongly associated with cellular physiological mechanisms and implicated in the numerous diseases. By exploring the subcellular localizations of lncRNAs, we can not only gain crucial insights into the molecular mechanisms of lncRNA-related biological processes but also make valuable contributions towards the diagnosis, prevention, and treatment of various human diseases. However, conventional experimental techniques tend to be laborious and time-intensive.
View Article and Find Full Text PDFThe built and natural environment can facilitate (un)healthy behaviors in adolescence. However, most previous studies have focused on examining associations between singular aspects of the environment. This study examined the association between the mixture of health-promoting and health-constraining environmental features in a Healthy Location Index (HLI) and physical activity and screen time among adolescents.
View Article and Find Full Text PDFTowards a critical posthumanist perspective on participatory design.
Med Humanit
January 2025
English, University of Leeds, Leeds, UK.
Participatory design places a strong emphasis on human agency, user perspectives and democratic ideals of inclusivity and empowerment, and is therefore often associated with humanist principles and values. In contrast, critical posthumanism questions key humanist assumptions about the centred and singular nature of the 'human condition'. Instead, posthumanism points to the evolving and diverse lived experiences of people and how these are transformed by (and are transforming of) culture, environment and technology.
View Article and Find Full Text PDFInflammatory Markers and Measures of Cardiovascular Autonomic Neuropathy in Type 1 Diabetes.
J Am Heart Assoc
December 2024
Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes University of Michigan Ann Arbor MI USA.
Background: Cardiovascular autonomic neuropathy (CAN) and inflammation predict more severe outcomes in type 1 diabetes (T1D). However, the link between CAN and inflammation in T1D remains unclear. We examined associations between CAN measures and inflammatory biomarkers in individuals with T1D.
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