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Antiproliferative and antiviral activity of methanolic extracts from Sardinian Maltese Mushroom ( L.). | LitMetric

AI Article Synopsis

  • The study investigates a non-photosynthetic plant commonly found in Mediterranean regions, known for its use in traditional medicine, focusing on its chemical and biological properties.
  • Researchers aimed to assess the plant's potential antiviral and antiproliferative effects using various cell assays, including the MTT assay and plaque reduction tests.
  • Results indicated that while the plant extract did not show selective activity against DNA or RNA viruses, it exhibited notable antiproliferative effects against human leukemia-derived cancer cells.

Article Abstract

is a non-photosynthetic plant that grows in Mediterranean countries and that is amply used in the traditional medicine. The aim of this study was to extend previous studies on the chemical and biological properties of evaluating the potential antiviral and antiproliferative activity of the methanolic extract. The MTT assay was used for the cytotoxic studies against human cancer-derived cell lines, while both MTT and plaque reduction (PRT) methods were used to evaluate the potential inhibitory effect of the extract against a panel of mammal viruses. The results obtained showed no selective activity against any DNA and RNA virus but revealed an interesting antiproliferative activity against human leukaemia-derived cell lines.

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Source
http://dx.doi.org/10.1080/14786419.2019.1678613DOI Listing

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