To Evaluate Choroidal and Retinal Thicknesses in Singleton versus Twin Pregnancies using Optical Coherence Tomography.

Purpose: The purpose of the study was to evaluate the choroidal and retinal thicknesses in singleton versus twin pregnancies.

Materials And Methods: This study included 20 single and 20 twin pregnant women in their 3 trimester with 20 age-matched healthy nonpregnant women as a control group. All participants underwent a detailed ocular examination. Cirrus enhanced depth imaging-optical coherence tomography was used for choroidal thickness (CT) with frame enhancement software. The study was divided into three groups: Group 1 - singleton pregnancy, Group 2 - twin pregnancy, and Group 3 - healthy nonpregnant controls. CT was measured from nasal, subfoveal, and temporal fields.

Results: Regarding CT, the twin pregnancy group had the thickest choroid followed by the singleton pregnancy group and control group. There was a statistically significant difference between Group 2 and Group 3 in terms of nasal, subfoveal, and temporal CTs ( = 0.002, = 0.001, and = 0.003, respectively). There was a statistically significant difference between Group 1 and Group 3 regarding just subfoveal CT ( = 0.028). Regarding retinal thickness, there was a statistically significant difference between Group 1 and Group 3 regarding the mean macular volume and ganglion cell-inner plexiform layer thicknesses ( < 0.05). Furthermore, regarding mean retinal nerve fiber layer thickness, there was a statistically significant difference between Group 1 and Group 2 and between Group 2 and Group 3 ( = 0.004, = 0.003, respectively).

Conclusion: Our study is the first one which evaluates choroidal and retinal thicknesses in twin pregnancies. We found that there was an increase in CT in the 3 trimester of pregnancies and it was prominent in twin pregnancies.