Diabetes mellitus (DM) greatly impacts human health worldwide as over 400 million patients suffer from DM-related symptoms. Type 2 DM accounts for more than 90% of DM and is caused mainly by unhealthy lifestyles, such as high-calorie and high-fat diets. Such undesirable eating habitats induce resistance to insulin resulting in high blood sugar levels that cause induction of various symptoms and complications of DM. Therefore, management of blood sugar levels is important for preventing DM. Our group has recently found that rice (Oryza sativa L.) contains anti-diabetes compounds. Here, we summarize the effect of the bioactive ingredients in rice on preventing type 2 DM.
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http://dx.doi.org/10.3177/jnsv.65.S113 | DOI Listing |
Heliyon
January 2025
Research Center for Pharmaceutical Ingredients and Traditional Medicine, National Research and Innovation Agency (BRIN), Complex Cibinong Science Center-BRIN, Cibinong, 16911, Jawa Barat, Indonesia.
The escalating concerns about the environmental and health impacts of synthetic pesticides have intensified the search for sustainable and effective alternatives. Cinnamon oil, derived from the bark of Cinnamomum species, has emerged as a promising candidate in this arena due to its potent biopesticidal properties. This review explores the multifaceted role of cinnamon oil in agricultural pest management, emphasizing its potential to contribute significantly to food security.
View Article and Find Full Text PDFJ Ovarian Res
January 2025
Department of Reproductive Medicine Center, Second Affiliated Hospital of Naval Medical University, Shanghai, 200003, China.
Background: Polycystic ovary syndrome (PCOS) is an endocrine disease associated with reproductive and metabolic abnormalities. The aim of this study was to elucidate the effects of Schisandra rubriflora (S. rubriflora) on PCOS and its related mechanisms using network pharmacology, molecular docking and in vitro experiments.
View Article and Find Full Text PDFInt Immunopharmacol
January 2025
Department of Orthopaedics, Shanghai Jing'an District Zhabei Central Hospital, Shanghai 200070 China. Electronic address:
Background And Objectives: Intervertebral disc degeneration (IVDD) is a complex condition that necessitates the development of novel therapeutic strategies. The objective of this study was to investigate the therapeutic potential of Fuzi decoction (FZD) in the treatment of IVDD by examining its bioactive components, target genes, molecular interactions, pathways, and therapeutic efficacy.
Methods: Bioactive ingredients with an oral bioavailability (OB) of ≥ 30 % and drug likeness (DL) of ≥ 0.
Heliyon
January 2025
Department of Food Science and Engineering, Hamedan Branch, Islamic Azad University, Hamedan, Iran.
Supercritical CO modified by polar solvents can extract a wide variety of polar and non-polar chemical components compared to conventional methods. The current study aims to extract Rivas (Rheum ribes) flower using the ethanol modified supercritical CO (SCO-EOH) method; analyze its chemical compounds and bioactivity, encapsulate the extract in maltodextrin, gum-Arabic (GA), and their combination (GA + MD) using the spray drying method and investigate the differences among microparticles using Principal Component Analysis (PCA). The Rivas extract obtained by the SCO-EOH method was a rich source of unsaturated fatty acids (mainly linoleic acid: 57.
View Article and Find Full Text PDFPlant Foods Hum Nutr
January 2025
College of Food Science and Engineering, Ningbo University, Ningbo, 315832, PR China.
Quinoa polysaccharides have attracted significant research interest in recent years due to their diverse biological activities, including antiviral, anti-inflammatory, antioxidant, and immunoregulatory properties. These attributes align with the growing global demand for natural, functional food ingredients, positioning quinoa polysaccharides as a valuable resource in food science and technology. This review presents an overview of the various bioactivities of quinoa polysaccharides, critically evaluates the methods used for their extraction and purification, describes their structural characteristics, and discusses their practical applications across multiple areas within the food industry, including food additives, meat products, health foods, and innovative food packaging.
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