Essential Oils and Their Natural Active Compounds Presenting Antifungal Properties.

Molecules

Laboratoire Stress Immunité Pathogènes, EA7300, Faculté de Médecine, 9 avenue de la Forêt de Haye, 54505 Vandoeuvre-les-Nancy, France.

Published: October 2019

The current rise in invasive fungal infections due to the increase in immunosuppressive therapies is a real concern. Moreover, the emergence of resistant strains induces therapeutic failures. In light of these issues, new classes of antifungals are anticipated. Therefore, the plant kingdom represents an immense potential of natural resources to exploit for these purposes. The aim of this review is to provide information about the antifungal effect of some important essential oils, and to describe the advances made in determining the mechanism of action more precisely. Finally, the issues of toxicity and resistance of fungi to essential oils will be discussed.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6832927PMC
http://dx.doi.org/10.3390/molecules24203713DOI Listing

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