New Microbe Killers: Self-Assembled Silver(I) Coordination Polymers Driven by a Cagelike Aminophosphine.

New Ag(I) coordination polymers, formulated as [Ag(-PTAH)(NO)] () and [Ag(-PTA)(NO)] (), were self-assembled as light- and air-stable microcrystalline solids and fully characterized by NMR and IR spectroscopy, electrospray ionization mass spectrometry (ESI-MS(±), elemental analysis, powder (PXRD) and single-crystal X-ray diffraction. Their crystal structures reveal resembling 1D metal-ligand chains that are driven by the 1,3,5-triaza-7-phospaadamantane (PTA) linkers and supported by terminal nitrate or nitrite ligands; these chains were classified within a topological type. Additionally, the structure of features a 1D→2D network extension through intermolecular hydrogen bonds, forming a two-dimensional hydrogen-bonded network with topology. Furthermore, both products and exhibit remarkable antimicrobial activity against different human pathogen bacteria (, , ) and yeast (), which is significantly superior to the activity of silver(I) nitrate as a reference topical antimicrobial.