AI Article Synopsis
- Researchers are studying how individual traits, like personality, can affect the success of a treatment called rTMS, which is used for stress-related disorders.
- In a study, 38 healthy women were stressed and then received two brain stimulation sessions to see how their mood and stress hormones changed.
- The results showed that while the sessions didn't change mood much, a personality trait called Cooperativeness helped reduce stress hormone levels after the treatment.
Article Abstract
Over the last years, individualization of repetitive Transcranial Magnetic Stimulation (rTMS) parameters has been a focus of attention in the field of non-invasive stimulation. It has been proposed that in stress-related disorders personality characteristics may influence the clinical outcome of rTMS. However, the underlying physiological mechanisms as to how personality may affect the rTMS response to stress remains to be clarified. In this sham-controlled crossover study, after being stressed by the Trier Social Stress Test, 38 healthy females received two sessions of intermittent theta burst stimulation (iTBS) applied to the left dorsolateral prefrontal cortex. To take possible personality influences into account, they also completed the Temperament and Character Inventory. Mood and salivary cortisol were assessed throughout the experimental protocol. Overall, two iTBS sessions did not significantly alter mood or influenced cortisol secretion. When taking into account personality features, higher scores on the character dimension Cooperativeness was related to decreased cortisol output, only when active iTBS was administered after the social stressor. In line with other studies, personality features such as the character dimension Cooperativeness may be of particular interest to explain individual neurobiological responses to neurostimulation.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6795454 | PMC |
| http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0223927 | PLOS |
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