Lower back pain is quite harmful to a person’s quality of life. It is mainly associated to skeletal-muscle injury and intervertebral disc displacement. Actions directed to avoid the burden of excessive weight, acquire exercise habits, preserve an ideal body weight, and procure postural hygiene, should be encouraged in children and adolescents.
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Best Pract Res Clin Rheumatol
January 2025
ICMR-National Institute of Research in Tribal Health, Jabalpur, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, India; Model Rural Health Research Unit, Jheet, Durg, India. Electronic address:
Sickle cell disease (SCD) is a mono-genic disorder causing chronic hemolysis, anemia, and vaso-occlusion, leading to musculoskeletal complications such as osteonecrosis, osteoporosis, and bone fractures affecting 50-70% SCD patients. These complications result from a complex interplay of genetic and physiological factors, including abnormal hemoglobin production, chronic inflammation, and oxidative stress. This review discusses the pathophysiology, pre-clinical symptoms, and clinical manifestations of musculoskeletal complications in SCD, as well as current treatment options, including pharmacological interventions, surgical procedures, and bone marrow transplantation.
View Article and Find Full Text PDFTissue Cell
January 2025
Center for Global health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India; Applied Biomedical Research Center, Mashhad University of Medical Sciences, Mashhad, Iran; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address:
Mobility disability is a common condition affecting older adults, making walking and the performance of activities of daily living difficult. Frailty, cachexia and sarcopenia are related conditions that occur with advancing age and are characterized by a decline in muscle mass, strength, and functionality that negatively impacts health. Chronic low-grade inflammation is a significant factor in the onset and progression of these conditions.
View Article and Find Full Text PDFJSES Int
November 2024
LAM - Motion Lab, University of Liège, Liège, Belgium.
Background: Musculoskeletal adaptations are common in overhead athletes. As they also are involved in injury prevention, there has been an increase in their evaluation through shoulder screening over the last years. However, for some evaluations, and especially for functional testing, there is a lack of normative values, which limits the interpretation of the values measured.
View Article and Find Full Text PDFJ Oral Rehabil
January 2025
Research Institute for Korean Medicine, Pusan National University, Yangsan, Republic of Korea.
Background: Early identification of penetration/aspiration (P/A) risk in older adults with sarcopenia is crucial to prevent complications and maintain quality of life.
Purpose: To evaluate the diagnostic utility of orofacial muscle strength measurements for predicting the risk of P/A in older adults with sarcopenia.
Methods: In this observational and prospective study, we collated consecutive data from community-dwelling older adults diagnosed with sarcopenia at a musculoskeletal disorder clinic.
Mod Rheumatol
January 2025
Department of Preventive Medicine for Locomotive Organ Disorders, 22nd Century Medical and Research Center, Faculty of Medicine, University of Tokyo, Tokyo, Japan.
Objectives: This study aimed to investigate the prevalence of radiographic hand osteoarthritis (HOA) in older Japanese individuals in three distinct regions with unique geographic and occupational characteristics and explore the regional variations and factors, including occupational workload, that affect HOA.
Methods: We analysed the radiographic images and data of 1642 participants aged ≥60 years (mean, 75.6 years).
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