To identify the exact molecular markers related to coronary slow flow syndrome (CSFS) and its prognosis. Data from 54 patients with CSFS diagnosed by coronary angiography and 101 normal control patients were collected and analyzed. Logistic regression analysis confirmed that homocysteine (Hcy; odds ratio: 1.107; 95% CI: 1.018-1.205; p = 0.018) was associated with CSFS. Receiver-operating characteristic curve analysis identified an Hcy value of 17.1 μmol/l as an effective cut-off point for predicting CSFS. Cox survival analysis showed a relationship between high admission Hcy level (odds ratio: 1.19; 95% CI = 1.05-1.34; p = 0.005) and recurrent angina. Our results showed positive correlations of Hcy with CSFS and cardiac events.

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http://dx.doi.org/10.2217/bmm-2018-0446DOI Listing

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