Introduction: In the United States, most women presenting in spontaneous labor undergo intravenous (IV) cannulation on admission to hospital labor and birth units. There is limited evidence for this routine practice in pregnant women at low risk for adverse outcomes during labor or birth.
Methods: A retrospective, exploratory, descriptive study of an indication-only practice of IV cannulation on admission for women presenting in spontaneous labor and cared for by a nurse-midwife service was performed. Descriptive data included the timing of IV cannula placement (admission, during labor or postpartum period, or not at all) and indications for placement. Maternal outcomes of interest were estimated blood loss, postpartum hemorrhage rates, and management; neonatal outcome was 5-minute Apgar scores.
Results: Records for 1069 women cared for by nurse-midwives who presented in spontaneous labor were reviewed. In this cohort, 445 (41.6%) had IV access established on admission, 325 (30.4%) had an IV cannula placed during labor or postpartum, and 299 (28%) never had IV access during their hospital stay. For the 325 women with IV cannulas placed after admission, 25 (7.7%) were placed urgently for excessive postpartum bleeding. Further analysis of the subset of women who had a postpartum hemorrhage after vaginal birth (defined as >500 mL estimated blood loss) indicated that urgent IV cannulation was not associated with a lower mean postpartum hemoglobin or hematocrit or an increase in blood transfusion rate when compared with women who had an IV cannula placed earlier in their labor course.
Discussion: Indication-only IV cannulation for women experiencing an uncomplicated labor and birth is a reasonable practice in settings where IV access can be established urgently if needed.
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http://dx.doi.org/10.1111/jmwh.13046 | DOI Listing |
J Am Chem Soc
January 2025
School of Chemistry, University of Leeds, Leeds LS2 9JT, U.K.
Ferroelectric nematic (N) liquid crystals combine liquid-like fluidity and orientational order of conventional nematics with macroscopic electric polarization comparable in magnitude to solid-state ferroelectric materials. Here, we present a systematic study of twenty-seven homologous materials with various fluorination patterns, giving new insight into the molecular origins of spontaneous polar ordering in fluid ferroelectric nematics. Beyond our initial expectations, we find the highest stability of the N phase to be in materials with specific fluorination patterns rather than the maximal fluorination, which might be expected based on simple models.
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December 2024
Stanford University, Palo Alto, CA, United States.
Background: Patients with cirrhosis are susceptible to infections due to abnormalities in humoral and cell-mediated immunity. Fungal infections are associated with delayed diagnosis and high mortality rates, emphasizing the importance of performing fungal cultures and maintaining elevated levels of suspicion in this patient population.
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J Endocr Soc
January 2025
Division of Pediatric Endocrinology, Hadassah Medical Center, Jerusalem 91240, Israel.
Context: Despite a growing number of studies, the genetic etiology in many cases of ovarian dysgenesis is incompletely understood.
Objectives: This work aimed to study the genetic etiology causing absence of spontaneous pubertal development, hypergonadotropic hypogonadism, and primary amenorrhea in 2 sisters.
Methods: Whole-exome sequencing was performed on DNA extracted from peripheral lymphocytes of 2 Palestinian sisters born to consanguineous parents.
Heliyon
January 2025
Department of Intelligent and Control Systems, Kyushu Institute of Technology, Iizuka, Fukuoka, 820-8502, Japan.
Spontaneous capillary flow in rectangular microfluidic channels is employed in microfluidic devices for various applications. The exact solution for flow in a rectangular cross-sectional channel has a complex point that contains an infinite sum term. The flow depends on the depth-width ratio of the rectangular channel's cross-section, .
View Article and Find Full Text PDFFood Res Int
February 2025
Analysis and Testing Center, Jiangnan University, Wuxi 214122, China. Electronic address:
The aim of this study was to isolate strains with excellent fermentation performance from pickles, thus enhancing the quality of rapid, low-salt fermented mustard leaves (Brassica juncea var. multiceps) through process optimization and inoculation fermentation. A high-throughput screening method for acid-producing strains was developed, significantly improving screening efficiency.
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