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Allergic Contact Dermatitis From Colophonium in Upholstery Adhesive: Two Case Reports of a Novel Source.
Contact Dermatitis
January 2025
Department of Dermatology and Venereology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Türkiye.
Relationship between antihistamine residues in wastewater and airborne pollen concentrations: Insights into population-scale pollinosis response.
Sci Total Environ
January 2025
Swiss Federal Institute of Aquatic Science and Technology, Eawag, Dübendorf, Switzerland.
Pollinosis is the most prevalent allergic disorder. Assessing the impact of real-world pollen exposure on symptoms remains challenging due to extensive patient-level efforts required. This study explores the potential of wastewater-based epidemiology (WBE) to investigate the relationship between airborne pollen concentrations and antihistamine residues in wastewater as an indicator of pollinosis symptom treatment at the population-scale.
View Article and Find Full Text PDFMolecular Signatures of Aeroallergen Sensitization in Respiratory Allergy: A Comparative Study Across Climate-Matched Populations.
Int J Mol Sci
December 2024
Inmunotek SL Laboratories, 28000 Madrid, Spain.
Climate change is significantly altering the dynamics of airborne allergens, affecting their seasonality, allergenicity, and geographic distribution, which correlates with increasing rates of allergic diseases. This study investigates aeroallergen sensitization among populations from Tenerife, Spain, and Lima, Peru-two regions with similar climates but distinct socio-economic conditions. Our findings reveal that Spanish individuals, particularly those with asthma, demonstrate higher sensitization levels to a broader range of allergens, especially mites, with 85% of participants reacting to at least one mite allergen.
View Article and Find Full Text PDFDiversity and Composition of the Airborne Fungal Community in Mexico City with a Metagenomic Approach.
Microorganisms
December 2024
Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México (UNAM), Circuito Exterior s/n, Coyoacán, Ciudad Universitaria, Mexico City 04510, Mexico.
Airborne fungi are widely distributed in the environment and originate from various sources like soil, plants, decaying organic matter, and even indoor environments. Exposure to airborne fungal spores can cause allergic reactions, asthma, and respiratory infections. Certain fungi can cause serious infections, particularly in individuals with weakened immune systems.
View Article and Find Full Text PDFIL-4R and CXCR2 Contribute to Downregulating Neutrophil-Mediated Response in the Early Stage of Fungal Extract-Induced Allergic Airway Inflammation.
Biomedicines
November 2024
Department of Immunology, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
: Airborne exogenous antigen inhalation can induce neutrophil infiltration of the airways, while eosinophils migrate to the airways in allergic airway inflammation. During a bacterial infection, Th2-associated cytokine IL-4, by binding to the IL-4 receptor (IL-4R), can suppress neutrophil recruitment to the site of inflammation. In the present study, we estimated whether the IL-4-dependent suppression of neutrophil recruitment contributed to the development of an immune response in asthma.
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