We employ some of the machinery developed in previous work to investigate the inferential and memory functions of quantum-like neural networks. We set up a logical apparatus to implement this in the form of a Gentzen sequent calculus which codifies some of the combinatory rules for the state spaces of the neuronal networks introduced earlier. We discuss memory storage in this context and along the way find formal proof that synchronicity promotes binding and storage. These results lead to an algorithmic fragment in calculus that simulates the memory function known as pattern completion. This claim is tested by noting that the failure of certain steps in the algorithm leads to memory deficits essentially identical to those found in such pathologies as Alzheimer's dementia, schizophrenia, and certain forms of autism. Moreover, a specific "power-of-two" wiring architecture and computational logic, which have been postulated and observed across many brain circuits, emerge spontaneously from our model. We draw conclusions concerning the possible nature of such mental processes qua computations.
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http://dx.doi.org/10.1007/s10867-019-09532-6 | DOI Listing |
Brain Behav Immun
January 2025
Neuropsychiatry Centre, The Royal Melbourne Hospital, Melbourne, Australia; Department of Psychiatry, University of Melbourne, Melbourne, Australia. Electronic address:
Int Psychogeriatr
January 2025
Department of Psychology, Lehman College/City University of New York, Bronx, NY 10468, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:
Objectives: Depression is a chronic disorder that significantly affects functional decline in older adults, especially those with type 2 diabetes (T2D). Ethnic groups may experience different depression risks and severities, yet the effect of ethnicity on depression trajectories and specific dimensions in older adults with T2D remains largely unexamined. We examined the longitudinal associations of ethnicity with depression and its specific dimensions over time in older Ashkenazi and non-Ashkenazi Jews with T2D.
View Article and Find Full Text PDFObjective: To explore the lived experiences and extent of cognitive symptoms in Long COVID (LC) in a UK-based sample.
Design: This study implemented a mixed-methods design. Eight focus groups were conducted to collect qualitative data, and the Framework Analysis was used to reveal the experiences and impact of cognitive symptoms.
Methods Cell Biol
January 2025
Federal University of Santa Maria, Center for Natural and Exact Sciences, Department of Biochemistry and Molecular Biology, Graduate Program in Biological Sciences: Toxicological Biochemistry, Camobi, Santa Maria, RS, Brazil.
Alzheimer's disease (AD) is the leading cause of dementia in the elderly, clinically characterized by memory loss, cognitive decline, and behavioral disturbances. Its pathogenesis is not fully comprehended but involves intracellular depositions of amyloid beta peptide (Aβ) and neurofibrillary tangles of hyperphosphorylated tau. Currently, pharmacological interventions solely slow the progression of symptoms.
View Article and Find Full Text PDFJ Prev Alzheimers Dis
February 2025
Neurology, Fondazione IRCCS "San Gerardo dei Tintori", Monza, Italy; Milan Center for Neuroscience (NeuroMI), University of Milano-Bicocca, Monza, Italy; Laboratory of Neurobiology, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy. Electronic address:
Background: The new criteria for Alzheimer's disease pave the way for the introduction of core blood biomarkers of Alzheimer's disease (BBAD) into clinical practice. However, this depends on the demonstration of sufficient accuracy and robustness of BBADs in the intended population.
Objectives: To assess the diagnostic performance of core BBADs in our memory clinic, comparing them with cerebrospinal fluid (CSF) analysis.
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