Objective: To develop and assess an equation based on maternal clinical parameters and third trimester ultrasound biometry (combined method), and compare it with ultrasound-estimated foetal weight (EFW) calculated using the Hadlock 2 formula.

Methods: Cohort study. A total of 1,224 women with singleton pregnancies who had undergone foetal ultrasound scanning (USS) at 34 weeks were recruited. The study was conducted at a reference center in Valencia (Spain) between January and December 2016. A gestation-adjusted projection (GAP) method was applied to estimated foetal-weight-for-gestational-age by foetal gender at delivery (EFWa). A multivariate regression was created to estimate foetal weight at term (EFWmr) using anthropometric, demographic, ultrasonographic and obstetric-neonatal variables. EFWa and EFWmr were calculated and compared with actual birthweight.

Results: The proportion for EFWmr within <10% of actual birthweight was greater than EFWa (82% vs. 65%, p<0.001). The mean relative error in foetal-weight predictions by using EFWmr was reduced from 6.7% to 0.9% (difference 5.7% 95% CI: 5.4 to 6.0) paired t-test p<0.001, significantly improving the accuracy attainable with USS. The EFWmr outperformed the GAP method in predicting birthweight, within 1% relative error. For new- borns <2,500 g, the proportion of estimates within <10% of the actual birthweight for the EFWmr was greater than that of the EFWa (20.4 vs. 16.3%, p=0.005). For babies with normal birthweight (2,500-3,999 g), EFWmr was a better predictor of birthweight than EFWa (84.5 vs. 65.7%, p<0.001).

Conclusions: Mathematical modelling to predict birthweight improves third trimester routine ultrasound measurement to estimate neonatal weight at term.

Download full-text PDF

Source
http://dx.doi.org/10.18597/rcog.3201DOI Listing

Publication Analysis

Top Keywords

third trimester
8
trimester ultrasound
8
cohort study
8
foetal weight
8
ultrasound scan
4
scan combined
4
combined clinical
4
clinical method
4
method accurate
4
accurate birthweight
4

Similar Publications

: Fluoxetine (FLX) is the inhibitor of serotonin reuptake most prescribed in pregnant women with depression. This study evaluates the influence of gestational diabetes mellitus (GDM) on the enantioselective pharmacokinetics and transplacental distribution of FLX and its metabolite norfluoxetine (norFLX). : Ten pregnant women diagnosed with GDM (GDM group) were investigated in the third trimester of gestation after they achieved good glycemic control.

View Article and Find Full Text PDF

Background/objectives: While studies in rat pups suggest that early zinc exposure is critical for optimal brain structure and function, associations of prenatal zinc intake with measures of brain development in infants are unknown. This study aimed to assess the associations of maternal zinc intake during pregnancy with MRI measures of brain tissue microstructure and neurodevelopmental outcomes, as well as to determine whether MRI measures of the brain mediated the relationship between maternal zinc intake and neurodevelopmental indices.

Methods: Forty-one adolescent mothers were recruited for a longitudinal study during pregnancy.

View Article and Find Full Text PDF

Smoking Status in Pregnancy: A Retrospective Analysis in Northern Greece.

J Clin Med

January 2025

Third Department of Obstetrics and Gynaecology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece.

Smoking has adverse effects on both maternal and fetal health and its incidence varies among different countries. The aim of this study was to identify the prevalence of smoking during pregnancy and to identify factors associated with smoking. This was a retrospective study conducted at the Third Department of Obstetrics and Gynecology, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece, during an 11-year period (2013-2023).

View Article and Find Full Text PDF

Women constitute most of the global horticulture workforce, where pesticide use is prevalent. Protecting their health, particularly during pregnancy, is essential. However, knowledge about practices among pregnant employees that cause exposure to pesticides is limited.

View Article and Find Full Text PDF

Clinical Care Pathways for Second and Third Trimester Termination of Pregnancy for Medical Reasons in Canada.

J Obstet Gynaecol Can

January 2025

University of British Columbia, Department of Obstetrics and Gynaecology, Vancouver, British Columbia, Canada. Electronic address:

Objective: Termination of pregnancy in the 2/3 trimester for fetal or maternal complications (i.e., for medical reasons) is an essential health service.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!