is an extensively drug-resistant opportunistic pathogen that can cause chronic otomastoiditis. There are no evidence-based treatment regimens for this severe infection. We treated four children with otomastoiditis with a structured regimen of topical imipenem and tigecycline, intravenous imipenem and tigecycline, and oral clofazimine and azithromycin and adjunctive surgery. This structured approach led to cure, with 1 year of follow-up after treatment. Adverse events were frequent, mostly caused by tigecycline.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7187624 | PMC |
| http://dx.doi.org/10.1128/AAC.01203-19 | DOI Listing |
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