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Constrictive bronchiolitis and paraneoplastic pemphigus caused by unicentric Castleman disease in a young woman: a case report.
Front Med (Lausanne)
October 2024
Department of Pulmonary and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Article Synopsis
- Constrictive bronchiolitis is a rare, severe condition causing irreversible small airway obstruction, potentially linked to an autoimmune syndrome stemming from Castleman disease.
- A 20-year-old female suffered from progressive breathing difficulties and oral sores, leading to an investigation that revealed a pelvic mass diagnosed as Castleman disease.
- Despite surgery to remove the mass alleviating some symptoms, she eventually required a lung transplant to significantly improve her lung function, highlighting the need for timely and thorough medical intervention.
[Rheumatoid arthritis with Castleman-like histopathology in lymph nodes: A case report].
Beijing Da Xue Xue Bao Yi Xue Ban
October 2024
Department of Rheumatology and Immunology, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China.
Rheumatoid arthritis (RA) is a common chronic autoimmune inflammatory disease, characterized by persistent polyarthritis. Patients with RA may exhibit varying degrees of B lymphocyte activation, clinically manifested as enlarged lymph nodes. Disease-modifying anti-rheumatic drugs and glucocorticoid are often used to treat RA.
View Article and Find Full Text PDFDiagnostic challenges in patients with Castleman disease, a single center experience from Hungary.
Pathol Oncol Res
September 2024
Division of Hematology, Department of Internal Medicine, University of Debrecen, Debrecen, Hungary.
Castleman disease is a rare and atypical lymphoproliferative disorder characterized by diverse clinical manifestations. It has both unicentric and multicentric forms, the latter with further subdivisions, i.e.
View Article and Find Full Text PDF[Paraneoplastic pemphigus with underlying Castleman's disease in a 16-year-old girl].
Dermatologie (Heidelb)
August 2024
Zentrum für Dermatologie, Allergologie und Dermatochirurgie, Helios Universitätsklinikum Wuppertal, Universität Witten/Herdecke, Heusnerstr. 40, 42283, Wuppertal, Deutschland.
Article Synopsis
- Paraneoplastic pemphigus is a severe autoimmune disease causing significant mucosal and skin lesions, and a case study is presented about a 16-year-old girl with early symptoms mistaken for mucosal pemphigoid.
- Initial treatment improved her condition, but she later faced severe respiratory issues linked to bronchiolitis obliterans, necessitating a lung transplant.
- During the evaluation for transplant, she was diagnosed with Castleman's disease, which led to the identification of paraneoplastic pemphigus, and both tumor removal and lung surgery resulted in positive outcomes and lasting remission.
Unicentric Castleman's disease in the parotid gland associated with psoriasis: a case report.
J Med Case Rep
April 2024
Department of Stomatology, Jinling Hospital, Affiliated Hospital of Medical School, Nanjing University, 305 East Zhongshan Road, Nanjing, 210012, Jiangsu, China.
Background: Castleman's disease is a rare lymphoproliferative disorder that is often misdiagnosed because of its untypical clinical or imaging features except for a painless mass. Besides, it is also difficult to cure Castleman's disease due to its unclear pathogenesis.
Case Presentation: We present a Castleman's disease case with diagnostic significance regarding a 54-year-old Chinese male who has a painless mass in his left parotid gland for 18 months with a 30-years history of autoimmune disease psoriasis.
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