Case: A 50-year-old female patient presented with significant (40%) bone loss of the lateral clavicle extending to the acromioclavicular (AC) joint, as a result of multiple, failed revision surgeries following a fracture-dislocation. She was treated with a free vascularized fibular graft and biplanar stabilization of the AC joint. At 4 years of follow-up, the patient had experienced resolution of painful symptoms with a Constant-Murley score of 72.
Conclusions: Reconstruction of large, lateral clavicle defects with a free vascularized fibular graft and biplanar stabilization of the AC joint may provide a satisfactory clinical outcome.
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http://dx.doi.org/10.2106/JBJS.CC.18.00330 | DOI Listing |
FEBS J
January 2025
INSERM UMR-1100, "Research Center for Respiratory Diseases (CEPR)", Tours, France.
Transplanted organs are inevitably exposed to ischemia-reperfusion (IR) injury, which is known to cause graft dysfunction. Functional and structural changes that follow IR tissue injury are mediated by neutrophils through the production of oxygen-derived free radicals, as well as from degranulation which entails the release of proteases and other pro-inflammatory mediators. Neutrophil serine proteases (NSPs) are believed to be the principal triggers of post-ischemic reperfusion damage.
View Article and Find Full Text PDFNeuroradiology
January 2025
Comprehensive Stroke Center, Department of Neuroscience, Hospital Clinic, Villarroel 170, 08036, Barcelona, Spain.
Purpose: Fluid exchanges between perivascular spaces (PVS) and interstitium may contribute to the pathophysiology of small vessel disease (SVD). We aimed to analyze water diffusivity measures and their relationship with PVS and other SVD imaging markers.
Methods: We enrolled 50 consecutive patients with a recent small subcortical infarct.
J Cardiovasc Dev Dis
December 2024
First Department of Cardiology, University Hospital of Ioannina, 455 00 Ioannina, Greece.
(1) Background: There are little data about the differences in clinical and echocardiographic characteristics between elderly (aged ≥ 65 years) and younger patients with acute pulmonary embolism (PE). (2) Methods: Consecutive patients diagnosed with PE in a tertiary hospital were identified. Clinical characteristics, biomarkers and transthoracic echocardiography indices including right ventricular free wall longitudinal strain (RV-FWLS) were recorded.
View Article and Find Full Text PDFCurr Oncol
December 2024
Otorhinolaryngology Unit, San Giovanni Bosco Hospital, 10154 Torino, Italy.
Early-stage laryngeal cancer (T1-T2) is commonly treated with organ-preserving techniques such as transoral laser microsurgery (TOLMS) or radiation therapy (RT), both providing comparable oncological outcomes but differing in functional results. Local recurrence occurs in approximately 10% of cases, making salvage surgery a crucial therapeutic option. This multi-institutional study investigates the efficacy of open partial horizontal laryngectomy (OPHL) as a salvage treatment, following recurrent laryngeal squamous-cell carcinoma (LSCC) after failed TOLMS.
View Article and Find Full Text PDFClin Pract
December 2024
Department of Maxillofacial Surgery, University Hospital of Split, 21000 Split, Croatia.
Radial forearm free flap (RFFF) is considered one of the workhorses in modern head and neck reconstruction surgery due to its technical simplicity, versatility and less time-consuming harvest. In this report, we present the case of a 56-year-old woman with sublingual squamous cell carcinoma (SCC) who underwent surgical resection and reconstruction of the defect with a RFFF. The preoperative Allen test showed normal blood flow, and the ultrasound did not recognize any blood vessel abnormalities in the left arm.
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