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In a proof-of-concept study, a mechano-chromic hydrogel was synthesized here, via chemoenzymatic click conjugation of fluorophore-labeled fibronectin into a synthetic hydrogel co-polymers (i.e., poly-N-isopropylacrylamide/polyethylene glycol). The optical FRET response could be tuned by macroscopic stretch.
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| http://dx.doi.org/10.1039/c9sm00380k | DOI Listing |
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Mechano-chromic protein-polymer hybrid hydrogel to visualize mechanical strain.
Soft Matter
November 2019
Laboratory of Applied Mechanobiology, Department of Health Sciences and Technology, ETH Zürich, Vladimir-Prelog-Weg 4, 8093 Zürich, Switzerland.
In a proof-of-concept study, a mechano-chromic hydrogel was synthesized here, via chemoenzymatic click conjugation of fluorophore-labeled fibronectin into a synthetic hydrogel co-polymers (i.e., poly-N-isopropylacrylamide/polyethylene glycol).
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